A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling

The current anti-cancer treatments are not enough to eradicate tumors, and therefore, new modalities and strategies are still needed. Most tumors generate an inflammatory tumor microenvironment (TME) and maintain the niche for their development. Because of the critical role of inflammation via high-...

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Detalles Bibliográficos
Autores principales: Tanuma, Sei-ichi, Oyama, Takahiro, Okazawa, Miwa, Yamazaki, Hiroaki, Takao, Koichi, Sugita, Yoshiaki, Amano, Shigeru, Abe, Takehiko, Sakagami, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998738/
https://www.ncbi.nlm.nih.gov/pubmed/35408786
http://dx.doi.org/10.3390/ijms23073426

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