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A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting
Counterfeiting drugs has been a global concern for years. Considering the lack of transparency within the current pharmaceutical distribution system, research has shown that blockchain technology is a promising solution for an improved supply chain system. This study aims to explore the current solu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998750/ https://www.ncbi.nlm.nih.gov/pubmed/35409774 http://dx.doi.org/10.3390/ijerph19074091 |
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author | Zoughalian, Kavyan Marchang, Jims Ghita, Bogdan |
author_facet | Zoughalian, Kavyan Marchang, Jims Ghita, Bogdan |
author_sort | Zoughalian, Kavyan |
collection | PubMed |
description | Counterfeiting drugs has been a global concern for years. Considering the lack of transparency within the current pharmaceutical distribution system, research has shown that blockchain technology is a promising solution for an improved supply chain system. This study aims to explore the current solution proposals for distribution systems using blockchain technology. Based on a literature review on currently proposed solutions, it is identified that the secrecy of the data within the system and nodes’ reputation in decision making has not been considered. The proposed prototype uses a zero-knowledge proof protocol to ensure the integrity of the distributed data. It uses the Markov model to track each node’s ‘reputation score’ based on their interactions to predict the reliability of the nodes in consensus decision making. Analysis of the prototype demonstrates a reliable method in decision making, which concludes with overall improvements in the system’s confidentiality, integrity, and availability. The result indicates that the decision protocol must be significantly considered in a reliable distribution system. It is recommended that the pharmaceutical distribution systems adopt a relevant protocol to design their blockchain solution. Continuous research is required further to increase performance and reliability within blockchain distribution systems. |
format | Online Article Text |
id | pubmed-8998750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89987502022-04-12 A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting Zoughalian, Kavyan Marchang, Jims Ghita, Bogdan Int J Environ Res Public Health Article Counterfeiting drugs has been a global concern for years. Considering the lack of transparency within the current pharmaceutical distribution system, research has shown that blockchain technology is a promising solution for an improved supply chain system. This study aims to explore the current solution proposals for distribution systems using blockchain technology. Based on a literature review on currently proposed solutions, it is identified that the secrecy of the data within the system and nodes’ reputation in decision making has not been considered. The proposed prototype uses a zero-knowledge proof protocol to ensure the integrity of the distributed data. It uses the Markov model to track each node’s ‘reputation score’ based on their interactions to predict the reliability of the nodes in consensus decision making. Analysis of the prototype demonstrates a reliable method in decision making, which concludes with overall improvements in the system’s confidentiality, integrity, and availability. The result indicates that the decision protocol must be significantly considered in a reliable distribution system. It is recommended that the pharmaceutical distribution systems adopt a relevant protocol to design their blockchain solution. Continuous research is required further to increase performance and reliability within blockchain distribution systems. MDPI 2022-03-30 /pmc/articles/PMC8998750/ /pubmed/35409774 http://dx.doi.org/10.3390/ijerph19074091 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zoughalian, Kavyan Marchang, Jims Ghita, Bogdan A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting |
title | A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting |
title_full | A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting |
title_fullStr | A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting |
title_full_unstemmed | A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting |
title_short | A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting |
title_sort | blockchain secured pharmaceutical distribution system to fight counterfeiting |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998750/ https://www.ncbi.nlm.nih.gov/pubmed/35409774 http://dx.doi.org/10.3390/ijerph19074091 |
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