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Smart Hydrogels for Advanced Drug Delivery Systems

Since the last few decades, the development of smart hydrogels, which can respond to stimuli and adapt their responses based on external cues from their environments, has become a thriving research frontier in the biomedical engineering field. Nowadays, drug delivery systems have received great atte...

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Detalles Bibliográficos
Autores principales: Bordbar-Khiabani, Aydin, Gasik, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998863/
https://www.ncbi.nlm.nih.gov/pubmed/35409025
http://dx.doi.org/10.3390/ijms23073665
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author Bordbar-Khiabani, Aydin
Gasik, Michael
author_facet Bordbar-Khiabani, Aydin
Gasik, Michael
author_sort Bordbar-Khiabani, Aydin
collection PubMed
description Since the last few decades, the development of smart hydrogels, which can respond to stimuli and adapt their responses based on external cues from their environments, has become a thriving research frontier in the biomedical engineering field. Nowadays, drug delivery systems have received great attention and smart hydrogels can be potentially used in these systems due to their high stability, physicochemical properties, and biocompatibility. Smart hydrogels can change their hydrophilicity, swelling ability, physical properties, and molecules permeability, influenced by external stimuli such as pH, temperature, electrical and magnetic fields, light, and the biomolecules’ concentration, thus resulting in the controlled release of the loaded drugs. Herein, this review encompasses the latest investigations in the field of stimuli-responsive drug-loaded hydrogels and our contribution to this matter.
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spelling pubmed-89988632022-04-12 Smart Hydrogels for Advanced Drug Delivery Systems Bordbar-Khiabani, Aydin Gasik, Michael Int J Mol Sci Review Since the last few decades, the development of smart hydrogels, which can respond to stimuli and adapt their responses based on external cues from their environments, has become a thriving research frontier in the biomedical engineering field. Nowadays, drug delivery systems have received great attention and smart hydrogels can be potentially used in these systems due to their high stability, physicochemical properties, and biocompatibility. Smart hydrogels can change their hydrophilicity, swelling ability, physical properties, and molecules permeability, influenced by external stimuli such as pH, temperature, electrical and magnetic fields, light, and the biomolecules’ concentration, thus resulting in the controlled release of the loaded drugs. Herein, this review encompasses the latest investigations in the field of stimuli-responsive drug-loaded hydrogels and our contribution to this matter. MDPI 2022-03-27 /pmc/articles/PMC8998863/ /pubmed/35409025 http://dx.doi.org/10.3390/ijms23073665 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bordbar-Khiabani, Aydin
Gasik, Michael
Smart Hydrogels for Advanced Drug Delivery Systems
title Smart Hydrogels for Advanced Drug Delivery Systems
title_full Smart Hydrogels for Advanced Drug Delivery Systems
title_fullStr Smart Hydrogels for Advanced Drug Delivery Systems
title_full_unstemmed Smart Hydrogels for Advanced Drug Delivery Systems
title_short Smart Hydrogels for Advanced Drug Delivery Systems
title_sort smart hydrogels for advanced drug delivery systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998863/
https://www.ncbi.nlm.nih.gov/pubmed/35409025
http://dx.doi.org/10.3390/ijms23073665
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