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Smart Hydrogels for Advanced Drug Delivery Systems
Since the last few decades, the development of smart hydrogels, which can respond to stimuli and adapt their responses based on external cues from their environments, has become a thriving research frontier in the biomedical engineering field. Nowadays, drug delivery systems have received great atte...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998863/ https://www.ncbi.nlm.nih.gov/pubmed/35409025 http://dx.doi.org/10.3390/ijms23073665 |
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author | Bordbar-Khiabani, Aydin Gasik, Michael |
author_facet | Bordbar-Khiabani, Aydin Gasik, Michael |
author_sort | Bordbar-Khiabani, Aydin |
collection | PubMed |
description | Since the last few decades, the development of smart hydrogels, which can respond to stimuli and adapt their responses based on external cues from their environments, has become a thriving research frontier in the biomedical engineering field. Nowadays, drug delivery systems have received great attention and smart hydrogels can be potentially used in these systems due to their high stability, physicochemical properties, and biocompatibility. Smart hydrogels can change their hydrophilicity, swelling ability, physical properties, and molecules permeability, influenced by external stimuli such as pH, temperature, electrical and magnetic fields, light, and the biomolecules’ concentration, thus resulting in the controlled release of the loaded drugs. Herein, this review encompasses the latest investigations in the field of stimuli-responsive drug-loaded hydrogels and our contribution to this matter. |
format | Online Article Text |
id | pubmed-8998863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89988632022-04-12 Smart Hydrogels for Advanced Drug Delivery Systems Bordbar-Khiabani, Aydin Gasik, Michael Int J Mol Sci Review Since the last few decades, the development of smart hydrogels, which can respond to stimuli and adapt their responses based on external cues from their environments, has become a thriving research frontier in the biomedical engineering field. Nowadays, drug delivery systems have received great attention and smart hydrogels can be potentially used in these systems due to their high stability, physicochemical properties, and biocompatibility. Smart hydrogels can change their hydrophilicity, swelling ability, physical properties, and molecules permeability, influenced by external stimuli such as pH, temperature, electrical and magnetic fields, light, and the biomolecules’ concentration, thus resulting in the controlled release of the loaded drugs. Herein, this review encompasses the latest investigations in the field of stimuli-responsive drug-loaded hydrogels and our contribution to this matter. MDPI 2022-03-27 /pmc/articles/PMC8998863/ /pubmed/35409025 http://dx.doi.org/10.3390/ijms23073665 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bordbar-Khiabani, Aydin Gasik, Michael Smart Hydrogels for Advanced Drug Delivery Systems |
title | Smart Hydrogels for Advanced Drug Delivery Systems |
title_full | Smart Hydrogels for Advanced Drug Delivery Systems |
title_fullStr | Smart Hydrogels for Advanced Drug Delivery Systems |
title_full_unstemmed | Smart Hydrogels for Advanced Drug Delivery Systems |
title_short | Smart Hydrogels for Advanced Drug Delivery Systems |
title_sort | smart hydrogels for advanced drug delivery systems |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998863/ https://www.ncbi.nlm.nih.gov/pubmed/35409025 http://dx.doi.org/10.3390/ijms23073665 |
work_keys_str_mv | AT bordbarkhiabaniaydin smarthydrogelsforadvanceddrugdeliverysystems AT gasikmichael smarthydrogelsforadvanceddrugdeliverysystems |