Targeting Protein Translation in Melanoma by Inhibiting EEF-2 Kinase Regulates Cholesterol Metabolism though SREBP2 to Inhibit Tumour Development

Decreasing the levels of certain proteins has been shown to be important for controlling cancer but it is currently unknown whether proteins could potentially be targeted by the inhibiting of protein synthesis. Under this circumstance, targeting protein translation could preferentially affect certai...

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Detalles Bibliográficos
Autores principales: Dinavahi, Saketh S., Chen, Yu-Chi, Gowda, Raghavendra, Dhanyamraju, Pavan Kumar, Punnath, Kishore, Desai, Dhimant, Berg, Arthur, Kimball, Scot R., Amin, Shantu, Yang, Jin-Ming, Robertson, Gavin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998919/
https://www.ncbi.nlm.nih.gov/pubmed/35408842
http://dx.doi.org/10.3390/ijms23073481

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