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NSAIDs Induce Proline Dehydrogenase/Proline Oxidase-Dependent and Independent Apoptosis in MCF7 Breast Cancer Cells

Non-steroidal anti-inflammatory drugs (NSAIDs) are considered in cancer therapy for their inhibitory effect on cyclooxygenase-2 (COX-2), which is overexpressed in most cancers. However, we found that NSAIDs as ligands of peroxisome proliferator-activated receptor-γ (PPARγ)-induced apoptosis independ...

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Detalles Bibliográficos
Autores principales: Kazberuk, Adam, Chalecka, Magda, Palka, Jerzy, Bielawska, Katarzyna, Surazynski, Arkadiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998922/
https://www.ncbi.nlm.nih.gov/pubmed/35409177
http://dx.doi.org/10.3390/ijms23073813

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