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Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts

Spinal muscular atrophy (SMA) is a severe, debilitating neuromuscular condition characterised by loss of motor neurons and progressive muscle wasting. SMA is caused by a loss of expression of SMN1 that encodes the survival motor neuron (SMN) protein necessary for the survival of motor neurons. Resto...

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Detalles Bibliográficos
Autores principales:	Toosaranont, Jarichad, Ruschadaariyachat, Sukanya, Mujchariyakul, Warasinee, Arora, Jantarika Kumar, Charoensawan, Varodom, Suktitipat, Bhoom, Palmer, Thomas N., Fletcher, Sue, Wilton, Steve D., Mitrpant, Chalermchai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999010/ https://www.ncbi.nlm.nih.gov/pubmed/35409296 http://dx.doi.org/10.3390/ijms23073937

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