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Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APP(swe) Alzheimer’s Disease Mouse Model

The free fatty acid FFA3 receptor (FFA3R) belongs to the superfamily of G-protein-coupled receptors (GPCRs). In the intestine and adipose tissue, it is involved in the regulation of energy metabolism, but its function in the brain is unknown. We aimed, first, to investigate the expression of the rec...

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Detalles Bibliográficos
Autores principales: Zamarbide, Marta, Martinez-Pinilla, Eva, Gil-Bea, Francisco, Yanagisawa, Masashi, Franco, Rafael, Perez-Mediavilla, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999053/
https://www.ncbi.nlm.nih.gov/pubmed/35408893
http://dx.doi.org/10.3390/ijms23073533

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