Cargando…

Eugenol β-Amino/β-Alkoxy Alcohols with Selective Anticancer Activity

Eugenol, 4-allyl-2-methoxyphenol, is the main constituent of clove essential oil and has demonstrated relevant biological activity, namely anticancer activity. Aiming to increase this activity, we synthesized a series of eugenol β-amino alcohol and β-alkoxy alcohol derivatives, which were then teste...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teixeira, Cláudia, Pereira, Renato B., Pinto, Nuno F. S., Coelho, Catarina M. M., Fernandes, Maria José G., Fortes, António G., Gonçalves, Maria S. T., Pereira, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999083/ https://www.ncbi.nlm.nih.gov/pubmed/35409123 http://dx.doi.org/10.3390/ijms23073759

Ejemplares similares

Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights
por: Pereira, Renato B., et al.
Publicado: (2021)

β-Amino- and Alkoxy-Substituted Disilanides
por: Balatoni, Istvan, et al.
Publicado: (2019)

New Eugenol Derivatives with Enhanced Insecticidal Activity
por: Fernandes, Maria José G., et al.
Publicado: (2020)

Exploring tailor-made Brønsted acid sites in mesopores of tin oxide catalyst for β-alkoxy alcohol and amino alcohol syntheses
por: Manjunathan, Pandian, et al.
Publicado: (2021)

Copper-Catalyzed Oxidative Cleavage of the C–C Bonds of β-Alkoxy Alcohols and β-1 Compounds
por: Kim, Si Ae, et al.
Publicado: (2020)

Liposomal Formulations Loaded with a Eugenol Derivative for Application as Insecticides: Encapsulation Studies and In Silico Identification of Protein Targets
por: Fernandes, Maria José G., et al.
Publicado: (2022)

Copper-catalyzed reactions of β-alkoxy/phenoxy enones with dimethyl diazomalonate
por: GÜNGÖR, Füsun Şeyma
Publicado: (2022)

Catalytic generation of alkoxy radicals from unfunctionalized alcohols
por: Tsui, Elaine, et al.
Publicado: (2020)

Anticancer Properties of Eugenol: A Review
por: Zari, Ali T., et al.
Publicado: (2021)

Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1
por: Herman, Bianka Edina, et al.
Publicado: (2019)

Synthesis of β-alkoxy-N-protected phenethylamines via one-pot copper-catalyzed aziridination and ring opening
por: Saavedra-Olavarría, Jorge, et al.
Publicado: (2018)

Alcohol Etherification via Alkoxy Radicals Generated by Visible-Light Photoredox Catalysis
por: Rivero, Alexandra R., et al.
Publicado: (2020)

The Flögel-three-component reaction with dicarboxylic acids – an approach to bis(β-alkoxy-β-ketoenamides) for the synthesis of complex pyridine and pyrimidine derivatives
por: Bera, Mrinal K, et al.
Publicado: (2014)

α,β‐Unsaturated Gold(I) Carbenes by Tandem Cyclization and 1,5‐Alkoxy Migration of 1,6‐Enynes: Mechanisms and Applications
por: Calleja, Pilar, et al.
Publicado: (2016)

Theoretical Study of the β-Cyclodextrin Inclusion Complex Formation of Eugenol in Water
por: Alvira, Elena
Publicado: (2018)

Assessment of host–guest molecular encapsulation of eugenol using β-cyclodextrin
por: de Freitas, Camila Auad Beltrão, et al.
Publicado: (2023)

Biological, pharmacological and immunological activities of novel 6-amino-acid-substituted 14-alkoxy-N-methylmorphinans
por: Guerrieri, Elena, et al.
Publicado: (2011)

Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
por: Ferraz da Costa, Danielly C., et al.
Publicado: (2020)

Fabrication and assessment of potent anticancer nanoconjugates from chitosan nanoparticles, curcumin, and eugenol
por: El-Sherbiny, Mohsen M., et al.
Publicado: (2022)

In vivo anticancer activity of benzoxazine and aminomethyl compounds derived from eugenol
por: Rudyanto, Marcellino, et al.
Publicado: (2023)

HEPATOTOXICITY OF EUGENOL
por: Soundran, Vijaya, et al.
Publicado: (1994)

New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation
por: Moreira, Joana, et al.
Publicado: (2018)

Enantioselective radical C–H amination for the synthesis of β-amino alcohols
por: Nakafuku, Kohki M., et al.
Publicado: (2020)

Efficient Protocol for Synthesis of β‐Hydroxy(alkoxy)selenides via Electrochemical Iodide‐Catalyzed Oxyselenation of Styrene Derivatives with Dialkyl(aryl)diselenides
por: Chen, Jinyang, et al.
Publicado: (2019)

Anticancer activities of a β-amino alcohol ligand and nanoparticles of its copper(ii) and zinc(ii) complexes evaluated by experimental and theoretical methods
por: Mardani, Zahra, et al.
Publicado: (2018)

AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF-β/Smad Signaling Pathway in Rats
por: Fathy, Moustafa, et al.
Publicado: (2020)

Multicomponent versus domino reactions: One-pot free-radical synthesis of β-amino-ethers and β-amino-alcohols
por: Rossi, Bianca, et al.
Publicado: (2015)

New carvacrol and thymol derivatives as potential insecticides: synthesis, biological activity, computational studies and nanoencapsulation
por: Natal, Carolina M., et al.
Publicado: (2021)

Synthesis of Isomers of Eugenol
por: Brauer, Gerhard M., et al.
Publicado: (1963)

Cyclization of 5-hexynoic acid to 3-alkoxy-2-cyclohexenones
por: Hylden, Anne T, et al.
Publicado: (2011)

Synthesis of C(70)-fragment buckybowls bearing alkoxy substituents
por: Yakiyama, Yumi, et al.
Publicado: (2020)

In vitro and in silico evaluation of the schistosomicidal activity of eugenol derivatives using biochemical, molecular, and morphological tools
por: de Souza, Isabella Maria Monteiro, et al.
Publicado: (2022)

Computational analysis of eugenol inhibitory activity in lipoxygenase and cyclooxygenase pathways
por: das Chagas Pereira de Andrade, Francisco, et al.
Publicado: (2020)

Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes
por: Begum, Zubeda, et al.
Publicado: (2020)

Synthesis of β-amino-α-trifluoromethyl alcohols and their applications in organic synthesis
por: Mlostoń, Grzegorz, et al.
Publicado: (2010)

Discovery of the Anticancer Activity for Lung and Gastric Cancer of a Brominated Coelenteramine Analog
por: González-Berdullas, Patricia, et al.
Publicado: (2022)

The Influence of Alkoxy Substitutions on the Properties of Diketopyrrolopyrrole-Phenyl Copolymers for Solar Cells
por: George, Zandra, et al.
Publicado: (2013)

Reaction between Peroxy and Alkoxy Radicals Can Form Stable Adducts
por: Iyer, Siddharth, et al.
Publicado: (2019)

Manganese-Catalyzed Electrochemical Deconstructive Chlorination of Cycloalkanols via Alkoxy Radicals
por: Allen, Benjamin D. W., et al.
Publicado: (2019)

Design, synthesis, and insecticidal activity of novel 1-alkoxy-2-nitroguanidines
por: Yang, Dongyan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bo06iiu0tdetisdsk3etirfm9d