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Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy

Management of coarctation of the aorta (CoA) during pregnancy is complicated by increased procedural risks to the pregnant woman and her fetus. The aim of this research was to analyze 10-years of experience of CoA treatment diagnosed during pregnancy. During 2010–2020 we performed percutaneous stent...

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Autores principales: Cherpak, Bogdan Volodymyrovych, Davydova, Yulia Volodymyrivna, Kravchenko, Vitalii Ivanovich, Yaschuk, Natalia Sergiivna, Siromakha, Sergii Olegovich, Lazoryshynets, Vasil Vasylovych
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999110/
https://www.ncbi.nlm.nih.gov/pubmed/35419094
http://dx.doi.org/10.25122/jml-2021-0363
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author Cherpak, Bogdan Volodymyrovych
Davydova, Yulia Volodymyrivna
Kravchenko, Vitalii Ivanovich
Yaschuk, Natalia Sergiivna
Siromakha, Sergii Olegovich
Lazoryshynets, Vasil Vasylovych
author_facet Cherpak, Bogdan Volodymyrovych
Davydova, Yulia Volodymyrivna
Kravchenko, Vitalii Ivanovich
Yaschuk, Natalia Sergiivna
Siromakha, Sergii Olegovich
Lazoryshynets, Vasil Vasylovych
author_sort Cherpak, Bogdan Volodymyrovych
collection PubMed
description Management of coarctation of the aorta (CoA) during pregnancy is complicated by increased procedural risks to the pregnant woman and her fetus. The aim of this research was to analyze 10-years of experience of CoA treatment diagnosed during pregnancy. During 2010–2020 we performed percutaneous stents implantations (SI) in 4 women during 15–23 weeks of pregnancy and in 6 women 48 hours – 5 years after delivery. In all presented cases, successful CoA repair was achieved. There was a significant decrease of peak-to-peak invasive systolic pressure gradient across the CoA (60.0±31.2 and 11.8±7.3 mmHg, p=0.001) and mean noninvasive systolic arterial pressure (163.0±46.2 and 120.5±9.2 mmHg, p=0.01) after SI. All percutaneously treated women during pregnancy (n=4) delivered healthy full-term babies. At follow-up (from 2 months to 10 years), all 10 women are alive without significant Doppler gradient across CoA with no signs of aortic aneurysm formation. To the best of our knowledge, we presented the largest published cohort of CoA percutaneous treatment during pregnancy. We categorized our experience in managing aortic coarctation diagnosed during pregnancy in one algorithm. Our experience demonstrates that excellent maternal and neonatal pregnancy outcomes can be obtained in women after CoA percutaneous repair, diagnosed during pregnancy. An aortic stent implantation is effective and safe for both mother and fetus.
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spelling pubmed-89991102022-04-12 Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy Cherpak, Bogdan Volodymyrovych Davydova, Yulia Volodymyrivna Kravchenko, Vitalii Ivanovich Yaschuk, Natalia Sergiivna Siromakha, Sergii Olegovich Lazoryshynets, Vasil Vasylovych J Med Life Original Article Management of coarctation of the aorta (CoA) during pregnancy is complicated by increased procedural risks to the pregnant woman and her fetus. The aim of this research was to analyze 10-years of experience of CoA treatment diagnosed during pregnancy. During 2010–2020 we performed percutaneous stents implantations (SI) in 4 women during 15–23 weeks of pregnancy and in 6 women 48 hours – 5 years after delivery. In all presented cases, successful CoA repair was achieved. There was a significant decrease of peak-to-peak invasive systolic pressure gradient across the CoA (60.0±31.2 and 11.8±7.3 mmHg, p=0.001) and mean noninvasive systolic arterial pressure (163.0±46.2 and 120.5±9.2 mmHg, p=0.01) after SI. All percutaneously treated women during pregnancy (n=4) delivered healthy full-term babies. At follow-up (from 2 months to 10 years), all 10 women are alive without significant Doppler gradient across CoA with no signs of aortic aneurysm formation. To the best of our knowledge, we presented the largest published cohort of CoA percutaneous treatment during pregnancy. We categorized our experience in managing aortic coarctation diagnosed during pregnancy in one algorithm. Our experience demonstrates that excellent maternal and neonatal pregnancy outcomes can be obtained in women after CoA percutaneous repair, diagnosed during pregnancy. An aortic stent implantation is effective and safe for both mother and fetus. Carol Davila University Press 2022-02 /pmc/articles/PMC8999110/ /pubmed/35419094 http://dx.doi.org/10.25122/jml-2021-0363 Text en ©2022 JOURNAL of MEDICINE and LIFE https://creativecommons.org/licenses/by/3.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Original Article
Cherpak, Bogdan Volodymyrovych
Davydova, Yulia Volodymyrivna
Kravchenko, Vitalii Ivanovich
Yaschuk, Natalia Sergiivna
Siromakha, Sergii Olegovich
Lazoryshynets, Vasil Vasylovych
Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
title Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
title_full Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
title_fullStr Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
title_full_unstemmed Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
title_short Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
title_sort management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999110/
https://www.ncbi.nlm.nih.gov/pubmed/35419094
http://dx.doi.org/10.25122/jml-2021-0363
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