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TKTL1 Knockdown Impairs Hypoxia-Induced Glucose-6-phosphate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase Overexpression

Increased expression of transketolase (TKT) and its isoform transketolase-like-1 (TKTL1) has been related to the malignant leukemia phenotype through promoting an increase in the non-oxidative branch of the pentose phosphate pathway (PPP). Recently, it has also been described that TKTL1 can have a r...

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Detalles Bibliográficos
Autores principales: Baptista, Inês, Karakitsou, Effrosyni, Cazier, Jean-Baptiste, Günther, Ulrich L., Marin, Silvia, Cascante, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999113/
https://www.ncbi.nlm.nih.gov/pubmed/35408935
http://dx.doi.org/10.3390/ijms23073574