Zafirlukast Induces VHL- and HIF-2α-Dependent Oxidative Cell Death in 786-O Clear Cell Renal Carcinoma Cells

Mutations in the Von Hippel–Lindau (VHL) gene are the driving force in many forms of clear cell renal cell carcinoma (ccRCC) and promote hypoxia-inducible factor (HIF)-dependent tumor proliferation, metastasis and angiogenesis. Despite the progress that has already been made, ccRCC generally remain...

Descripción completa

Detalles Bibliográficos
Autores principales: Wolf, Christopher, Smith, Sonja, van Wijk, Sjoerd J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999127/
https://www.ncbi.nlm.nih.gov/pubmed/35408930
http://dx.doi.org/10.3390/ijms23073567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999127/
https://www.ncbi.nlm.nih.gov/pubmed/35408930
http://dx.doi.org/10.3390/ijms23073567

Ejemplares similares