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Sensing the Messenger: Potential Roles of Cyclic-di-GMP in Rickettsial Pathogenesis

Pathogenic bacteria causing human rickettsioses, transmitted in nature by arthropod vectors, primarily infect vascular endothelial cells lining the blood vessels, resulting in ‘endothelial activation’ and onset of innate immune responses. Nucleotide second messengers are long presumed to be the stim...

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Detalles Bibliográficos
Autores principales: Narra, Hema P., Sahni, Abha, Sepuru, Krishna Mohan, Alsing, Jessica, Sahni, Sanjeev K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999164/
https://www.ncbi.nlm.nih.gov/pubmed/35409212
http://dx.doi.org/10.3390/ijms23073853