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Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies

The purpose of this study is to assess the effect of nine covariates on the occurrence or absence of stable or symptomatic pneumothorax. Forty-three patients underwent CT-guided lung biopsies from January 2020 to January 2022 (24 m, 19 f, median age 70 years). All the interventions were carried out...

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Autores principales: Maalouf, Nour, Lavric, Daniela, Vasileva, Lora, Lamadé, Wolfram, Apitzsch, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999419/
https://www.ncbi.nlm.nih.gov/pubmed/35407566
http://dx.doi.org/10.3390/jcm11071958
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author Maalouf, Nour
Lavric, Daniela
Vasileva, Lora
Lamadé, Wolfram
Apitzsch, Jonas
author_facet Maalouf, Nour
Lavric, Daniela
Vasileva, Lora
Lamadé, Wolfram
Apitzsch, Jonas
author_sort Maalouf, Nour
collection PubMed
description The purpose of this study is to assess the effect of nine covariates on the occurrence or absence of stable or symptomatic pneumothorax. Forty-three patients underwent CT-guided lung biopsies from January 2020 to January 2022 (24 m, 19 f, median age 70 years). All the interventions were carried out with a semi-automatic 18G needle and a 17G trocar in a prone or supine position. Different covariates were measured and correlated to the rate and severity of the pneumothoraces observed. Nominal two-sided t-test p-values for the continuous variables and Fisher’s exact test results for the categorical variables were conducted. The data included the lesion size, distance to the pleura, needle-pleura angle, age, gender, position during the procedure, and the presence of chronic obstructive pulmonary disease. Patients with an observed pneumothorax had an average angle between the needle and the pleura of 74.00° compared to 94.68° in patients with no pneumothorax (p-value = 0.028). A smaller angle measurement correlated with a higher risk of pneumothorax development. The needle-pleural angle plays a vital role in the outcome of a CT-guided lung biopsy. Correctly adjusting the needle-pleural angle can diminish the pneumothorax risk associated with a CT-guided lung biopsy. The study results show that as the needle’s angle deviates from the perpendicular, the pleural surface area experiencing trauma increases, and pneumothorax is more likely to occur.
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spelling pubmed-89994192022-04-12 Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies Maalouf, Nour Lavric, Daniela Vasileva, Lora Lamadé, Wolfram Apitzsch, Jonas J Clin Med Article The purpose of this study is to assess the effect of nine covariates on the occurrence or absence of stable or symptomatic pneumothorax. Forty-three patients underwent CT-guided lung biopsies from January 2020 to January 2022 (24 m, 19 f, median age 70 years). All the interventions were carried out with a semi-automatic 18G needle and a 17G trocar in a prone or supine position. Different covariates were measured and correlated to the rate and severity of the pneumothoraces observed. Nominal two-sided t-test p-values for the continuous variables and Fisher’s exact test results for the categorical variables were conducted. The data included the lesion size, distance to the pleura, needle-pleura angle, age, gender, position during the procedure, and the presence of chronic obstructive pulmonary disease. Patients with an observed pneumothorax had an average angle between the needle and the pleura of 74.00° compared to 94.68° in patients with no pneumothorax (p-value = 0.028). A smaller angle measurement correlated with a higher risk of pneumothorax development. The needle-pleural angle plays a vital role in the outcome of a CT-guided lung biopsy. Correctly adjusting the needle-pleural angle can diminish the pneumothorax risk associated with a CT-guided lung biopsy. The study results show that as the needle’s angle deviates from the perpendicular, the pleural surface area experiencing trauma increases, and pneumothorax is more likely to occur. MDPI 2022-04-01 /pmc/articles/PMC8999419/ /pubmed/35407566 http://dx.doi.org/10.3390/jcm11071958 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Maalouf, Nour
Lavric, Daniela
Vasileva, Lora
Lamadé, Wolfram
Apitzsch, Jonas
Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies
title Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies
title_full Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies
title_fullStr Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies
title_full_unstemmed Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies
title_short Associations between Covariates and Pneumothorax Observations in CT-Guided Lung Biopsies
title_sort associations between covariates and pneumothorax observations in ct-guided lung biopsies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999419/
https://www.ncbi.nlm.nih.gov/pubmed/35407566
http://dx.doi.org/10.3390/jcm11071958
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