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ADAMTS13, VWF, and Endotoxin Are Interrelated and Associated with the Severity of Liver Cirrhosis via Hypercoagulability

ADAMTS13 specifically cleaves the multimeric von Willebrand factor (VWF), and an imbalance between ADAMTS13 activity (ADAMTS13:AC) and VWF antigen (VWF:Ag) levels is associated with the severity of liver cirrhosis (LC). However, the reason for this imbalance in patients with LC is unknown. This stud...

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Detalles Bibliográficos
Autores principales: Takaya, Hiroaki, Namisaki, Tadashi, Asada, Shohei, Iwai, Satoshi, Kubo, Takahiro, Suzuki, Junya, Enomoto, Masahide, Tsuji, Yuki, Fujinaga, Yukihisa, Nishimura, Norihisa, Sawada, Yasuhiko, Kaji, Kosuke, Kawaratani, Hideto, Moriya, Kei, Akahane, Takemi, Matsumoto, Masanori, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999602/
https://www.ncbi.nlm.nih.gov/pubmed/35407443
http://dx.doi.org/10.3390/jcm11071835

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