Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls

Over the last two decades, indoleamine 2,3-dioxygenase 1 (IDO1) has attracted wide interest as a key player in immune regulation, fostering the design and development of small molecule inhibitors to restore immune response in tumor immunity. In this framework, biochemical, structural, and pharmacolo...

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Detalles Bibliográficos
Autores principales: Mammoli, Andrea, Bianconi, Elisa, Ruta, Luana, Riccio, Alessandra, Bigiotti, Carlo, Souma, Maria, Carotti, Andrea, Rossini, Sofia, Suvieri, Chiara, Pallotta, Maria Teresa, Grohmann, Ursula, Camaioni, Emidio, Macchiarulo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999677/
https://www.ncbi.nlm.nih.gov/pubmed/35409342
http://dx.doi.org/10.3390/ijms23073981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999677/
https://www.ncbi.nlm.nih.gov/pubmed/35409342
http://dx.doi.org/10.3390/ijms23073981

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