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Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls

Over the last two decades, indoleamine 2,3-dioxygenase 1 (IDO1) has attracted wide interest as a key player in immune regulation, fostering the design and development of small molecule inhibitors to restore immune response in tumor immunity. In this framework, biochemical, structural, and pharmacolo...

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Detalles Bibliográficos
Autores principales:	Mammoli, Andrea, Bianconi, Elisa, Ruta, Luana, Riccio, Alessandra, Bigiotti, Carlo, Souma, Maria, Carotti, Andrea, Rossini, Sofia, Suvieri, Chiara, Pallotta, Maria Teresa, Grohmann, Ursula, Camaioni, Emidio, Macchiarulo, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999677/ https://www.ncbi.nlm.nih.gov/pubmed/35409342 http://dx.doi.org/10.3390/ijms23073981

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