Cargando…

Anti-Inflammatory Activities of an Anti-Histamine Drug, Loratadine, by Suppressing TAK1 in AP-1 Pathway

Loratadine is an anti-histamine routinely used for treating allergies. However, recent findings have shown that Loratadine may also have anti-inflammatory functions, while their exact mechanisms have not yet been fully uncovered. In this paper, we investigated whether Loratadine can be utilized as a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jang, Jiwon, Hunto, Stephanie Triseptya, Kim, Ji Won, Lee, Hwa Pyoung, Kim, Han Gyung, Cho, Jae Youl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999734/ https://www.ncbi.nlm.nih.gov/pubmed/35409346 http://dx.doi.org/10.3390/ijms23073986

Ejemplares similares

TAK1/AP-1-Targeted Anti-Inflammatory Effects of Barringtonia augusta Methanol Extract
por: Ha, Anh Thu, et al.
Publicado: (2021)

Euodia pasteuriana Methanol Extract Exerts Anti-Inflammatory Effects by Targeting TAK1 in the AP-1 Signaling Pathway
por: Zhang, Jianmei, et al.
Publicado: (2020)

Phosphatidylinositide 3-Kinase Contributes to the Anti-Inflammatory Effect of Abutilon crispum L. Medik Methanol Extract
por: Hunto, Stephanie Triseptya, et al.
Publicado: (2018)

Tabebuia impetiginosa: A Comprehensive Review on Traditional Uses, Phytochemistry, and Immunopharmacological Properties
por: Zhang, Jianmei, et al.
Publicado: (2020)

Brain histamine H(1) receptor occupancy after oral administration of desloratadine and loratadine
por: Nakamura, Tadaho, et al.
Publicado: (2019)

Effects of loratadine, a histamine H(1) receptor antagonist, on the skeletal system of young male rats
por: Folwarczna, Joanna, et al.
Publicado: (2019)

AP-1-Targeting Anti-Inflammatory Activity of the Methanolic Extract of Persicaria chinensis
por: Hossen, Muhammad Jahangir, et al.
Publicado: (2015)

Korean Red Ginseng water extract inhibits cadmium-induced lung injury via suppressing MAPK/ERK1/2/AP-1 pathway
por: Mitra, Ankita, et al.
Publicado: (2022)

Loratadine, an H(1) Antihistamine, Inhibits Melanogenesis in Human Melanocytes
por: Moon, Hye-Rim, et al.
Publicado: (2019)

Olea europaea Suppresses Inflammation by Targeting TAK1-Mediated MAP Kinase Activation
por: Song, Chaoran, et al.
Publicado: (2021)

Anti-Inflammatory Activities of the Ethanol Extract of Prasiola japonica, an Edible Freshwater Green Algae, and Its Various Solvent Fractions in LPS-Induced Macrophages and Carrageenan-Induced Paw Edema via the AP-1 Pathway
por: Rahmawati, Laily, et al.
Publicado: (2021)

Anti-Inflammatory Effects of Licania macrocarpa Cuatrec Methanol Extract Target Src- and TAK1-Mediated Pathways
por: Shin, Kon Kuk, et al.
Publicado: (2019)

Dehydroabietic Acid Suppresses Inflammatory Response Via Suppression of Src-, Syk-, and TAK1-Mediated Pathways
por: Kim, Eunji, et al.
Publicado: (2019)

AP-1-Targeted Anti-Inflammatory Activities of the Nanostructured, Self-Assembling S5 Peptide
por: Yang, Woo Seok, et al.
Publicado: (2015)

Anti-Oxidative and Anti-Aging Effects of Ethanol Extract of the Officinal Breynia (Breynia vitis-idaea) In Vitro
por: Shin, Chae Yun, et al.
Publicado: (2023)

A Note on Histamine-Anti-Histaminic Drugs
por: Raychaudhury, A. K.
Publicado: (1951)

Angioedema suppressed by a combination of anti-histamine and leukotriene modifier
por: Wong, Brendan N., et al.
Publicado: (2017)

HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1
por: Liu, Ruikang, et al.
Publicado: (2014)

The TGF(β)→TAK1→LATS→YAP1 Pathway Regulates the Spatiotemporal Dynamics of YAP1
por: Kim, Min-Kyu, et al.
Publicado: (2023)

AP-1/IRF-3 Targeted Anti-Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata
por: Shen, Ting, et al.
Publicado: (2013)

Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice
por: Choi, Da-Som, et al.
Publicado: (2020)

Combining thioridazine and loratadine for the treatment of gastrointestinal tumor
por: Chen, Tingting, et al.
Publicado: (2017)

Antioxidant, Anti-Inflammatory, Anti-Menopausal, and Anti-Cancer Effects of Lignans and Their Metabolites
por: Jang, Won Young, et al.
Publicado: (2022)

Anti-Gastritis and Anti-Lung Injury Effects of Pine Tree Ethanol Extract Targeting Both NF-κB and AP-1 Pathways
por: Kim, Seung A, et al.
Publicado: (2021)

Improved survival in several cancers with use of H(1)-antihistamines desloratadine and loratadine
por: Fritz, Ildikó, et al.
Publicado: (2021)

ANTI HISTAMINIC ACTIVITY OF CISSUS QUADRAGULARIS
por: Begum, V. Hazeena, et al.
Publicado: (1999)

Development and evaluation of in situ nasal gel formulations of loratadine
por: Sherafudeen, Sheri Peedikayil, et al.
Publicado: (2015)

Loratadine inhibits Staphylococcus aureus virulence and biofilm formation
por: Zheng, Jinxin, et al.
Publicado: (2022)

Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef
por: Hashimoto, M, et al.
Publicado: (2014)

Phosphatase inhibition by sodium orthovanadate displays anti-inflammatory action by suppressing AKT-IKKβ signaling in RAW264.7 cells
por: Kim, Han Gyung, et al.
Publicado: (2022)

TAK1ng control: TAK1 restrains NLRP3 activation
por: Mangan, Matthew Stephen, et al.
Publicado: (2018)

TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1
por: Shin, Ju Hyun, et al.
Publicado: (2013)

Radical Scavenging Activity-Based and AP-1-Targeted Anti-Inflammatory Effects of Lutein in Macrophage-Like and Skin Keratinocytic Cells
por: Oh, Jueun, et al.
Publicado: (2013)

Dipterocarpus tuberculatus Roxb. Ethanol Extract Has Anti-Inflammatory and Hepatoprotective Effects In Vitro and In Vivo by Targeting the IRAK1/AP-1 Pathway
por: Kim, Haeyeop, et al.
Publicado: (2021)

Protein Arginine Methyltransferase 1 (PRMT1) Selective Inhibitor, TC-E 5003, Has Anti-Inflammatory Properties in TLR4 Signaling
por: Kim, Eunji, et al.
Publicado: (2020)

Histamine receptor antagonism and anti-tumour activity.
por: Collins, M., et al.
Publicado: (1982)

MMPP Exerts Anti-Inflammatory Effects by Suppressing MD2-Dependent NF-κB and JNK/AP-1 Pathways in THP-1 Monocytes
por: Kim, Seonhwa, et al.
Publicado: (2023)

Curcumin’s Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects in vivo Through Suppression of TAK1-NF-κB Pathway
por: Zhang, Zhen-Biao, et al.
Publicado: (2018)

Maternal use of Loratadine during pregnancy and risk of hypospadias in offspring
por: Pedersen, Lars, et al.
Publicado: (2006)

Loratadine-associated cystoid macular edema: A case report
por: Tang, Yong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sg132gsqbfqs2dlb9ofav19ksf