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Expression of Huntingtin and TDP-43 Derivatives in Fission Yeast Can Cause Both Beneficial and Toxic Effects

Many neurodegenerative disorders display protein aggregation as a hallmark, Huntingtin and TDP-43 aggregates being characteristic of Huntington disease and amyotrophic lateral sclerosis, respectively. However, whether these aggregates cause the diseases, are secondary by-products, or even have prote...

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Detalles Bibliográficos
Autores principales:	Marte, Luis, Boronat, Susanna, Barrios, Rubén, Barcons-Simon, Anna, Bolognesi, Benedetta, Cabrera, Margarita, Ayté, José, Hidalgo, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999813/ https://www.ncbi.nlm.nih.gov/pubmed/35409310 http://dx.doi.org/10.3390/ijms23073950

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