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Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements
This work reports on a new TBO–Pluronic F–127 three-dimensional (3D) gel dosimeter for UV light dose distribution measurements. The optimal gel composition was found to be 60 µM Toluidine Blue O (TBO), which acts as a UV-sensitive compound; 5% w/w hydrogen peroxide (H(2)O(2)), which is necessary for...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999840/ https://www.ncbi.nlm.nih.gov/pubmed/35407878 http://dx.doi.org/10.3390/ma15072546 |
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author | Jaszczak, Malwina Sąsiadek-Andrzejczak, Elżbieta Kozicki, Marek |
author_facet | Jaszczak, Malwina Sąsiadek-Andrzejczak, Elżbieta Kozicki, Marek |
author_sort | Jaszczak, Malwina |
collection | PubMed |
description | This work reports on a new TBO–Pluronic F–127 three-dimensional (3D) gel dosimeter for UV light dose distribution measurements. The optimal gel composition was found to be 60 µM Toluidine Blue O (TBO), which acts as a UV-sensitive compound; 5% w/w hydrogen peroxide (H(2)O(2)), which is necessary for initiation of TBO photodegradation and 25% w/w poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F–127), which forms a physical gel matrix. The dosimeter becomes discoloured when exposed to UV radiation and a discolouration is the more intense, the higher the absorbed dose is. The samples after irradiation with UVA, UVB and UVC radiation were measured using UV-Vis spectrophotometry to obtain the basic dose–response characteristic of the dosimeter, including dose sensitivity, linear and dynamic dose range, threshold dose, stability over time and dose–response for fractioned and non-fractioned doses. Additionally, the TBO–Pluronic F–127 gel dosimeter was investigated for spatial stability and the ability to measure the dose distribution of UV radiation. The results obtained indicate that the TBO–Pluronic F–127 dosimeter is a promising UV sensor and 2D/3D UV dosimeter. |
format | Online Article Text |
id | pubmed-8999840 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89998402022-04-12 Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements Jaszczak, Malwina Sąsiadek-Andrzejczak, Elżbieta Kozicki, Marek Materials (Basel) Article This work reports on a new TBO–Pluronic F–127 three-dimensional (3D) gel dosimeter for UV light dose distribution measurements. The optimal gel composition was found to be 60 µM Toluidine Blue O (TBO), which acts as a UV-sensitive compound; 5% w/w hydrogen peroxide (H(2)O(2)), which is necessary for initiation of TBO photodegradation and 25% w/w poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F–127), which forms a physical gel matrix. The dosimeter becomes discoloured when exposed to UV radiation and a discolouration is the more intense, the higher the absorbed dose is. The samples after irradiation with UVA, UVB and UVC radiation were measured using UV-Vis spectrophotometry to obtain the basic dose–response characteristic of the dosimeter, including dose sensitivity, linear and dynamic dose range, threshold dose, stability over time and dose–response for fractioned and non-fractioned doses. Additionally, the TBO–Pluronic F–127 gel dosimeter was investigated for spatial stability and the ability to measure the dose distribution of UV radiation. The results obtained indicate that the TBO–Pluronic F–127 dosimeter is a promising UV sensor and 2D/3D UV dosimeter. MDPI 2022-03-30 /pmc/articles/PMC8999840/ /pubmed/35407878 http://dx.doi.org/10.3390/ma15072546 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Jaszczak, Malwina Sąsiadek-Andrzejczak, Elżbieta Kozicki, Marek Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements |
title | Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements |
title_full | Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements |
title_fullStr | Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements |
title_full_unstemmed | Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements |
title_short | Discolouring 3D Gel Dosimeter for UV Dose Distribution Measurements |
title_sort | discolouring 3d gel dosimeter for uv dose distribution measurements |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999840/ https://www.ncbi.nlm.nih.gov/pubmed/35407878 http://dx.doi.org/10.3390/ma15072546 |
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