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Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degeneration

In this study, we used single-cell transcriptomic analysis to identify new specific biomarkers for nucleus pulposus (NP) and inner annulus fibrosis (iAF) cells, and to define cell populations within non-degenerating (nD) and degenerating (D) human intervertebral discs (IVD) of the same individual. C...

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Detalles Bibliográficos
Autores principales: Cherif, Hosni, Mannarino, Matthew, Pacis, Alain Sarabia, Ragoussis, Jiannis, Rabau, Oded, Ouellet, Jean A., Haglund, Lisbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999935/
https://www.ncbi.nlm.nih.gov/pubmed/35409356
http://dx.doi.org/10.3390/ijms23073993