Cargando…
Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study
Transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement. The aim of this study was to evaluate whether a relevant alteration in cerebral tissue oxygen saturation (rSO(2)) could be detected following TAVI. Retrospective data analysis included...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999949/ https://www.ncbi.nlm.nih.gov/pubmed/35407537 http://dx.doi.org/10.3390/jcm11071930 |
_version_ | 1784685313511129088 |
---|---|
author | Schmidt, Götz Kreissl, Hannes Vigelius-Rauch, Ursula Schneck, Emmanuel Edinger, Fabian Nef, Holger Böning, Andreas Sander, Michael Koch, Christian |
author_facet | Schmidt, Götz Kreissl, Hannes Vigelius-Rauch, Ursula Schneck, Emmanuel Edinger, Fabian Nef, Holger Böning, Andreas Sander, Michael Koch, Christian |
author_sort | Schmidt, Götz |
collection | PubMed |
description | Transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement. The aim of this study was to evaluate whether a relevant alteration in cerebral tissue oxygen saturation (rSO(2)) could be detected following TAVI. Retrospective data analysis included 275 patients undergoing TAVI between October 2016 and December 2020. Overall, rSO(2) significantly increased following TAVI (64.6 ± 10% vs. 68.1 ± 10%, p < 0.01). However, a significant rise was only observed in patients with a preoperative rSO(2) < 60%. Of the hemodynamic confounders studied, hemoglobin, mean arterial pressure and blood pH were lowered, while central venous pressure and arterial partial pressure of carbon dioxide (PaCO(2)) were slightly elevated (PaCO(2): 39 (36–43) mmHg vs. 42 (37–47) mmHg, p = 0.03; pH: 7.41 (7.3–7.4) vs. 7.36 (7.3–7.4), p < 0.01). Multivariate linear regression modeling identified only hemoglobin as a predictor of altered rSO(2). Patients with a EuroScore II above 4% and an extended ICU stay were found to have lower rSO(2), while no difference was observed in patients with postoperative delirium or between the implanted valve types. Further prospective studies that eliminate differences in potential confounding variables are necessary to confirm the rise in rSO(2). Future research should provide more information on the value of cerebral oximetry for identifying high-risk patients who will require further clinical interventions in the setting of the TAVI procedure. |
format | Online Article Text |
id | pubmed-8999949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89999492022-04-12 Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study Schmidt, Götz Kreissl, Hannes Vigelius-Rauch, Ursula Schneck, Emmanuel Edinger, Fabian Nef, Holger Böning, Andreas Sander, Michael Koch, Christian J Clin Med Article Transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement. The aim of this study was to evaluate whether a relevant alteration in cerebral tissue oxygen saturation (rSO(2)) could be detected following TAVI. Retrospective data analysis included 275 patients undergoing TAVI between October 2016 and December 2020. Overall, rSO(2) significantly increased following TAVI (64.6 ± 10% vs. 68.1 ± 10%, p < 0.01). However, a significant rise was only observed in patients with a preoperative rSO(2) < 60%. Of the hemodynamic confounders studied, hemoglobin, mean arterial pressure and blood pH were lowered, while central venous pressure and arterial partial pressure of carbon dioxide (PaCO(2)) were slightly elevated (PaCO(2): 39 (36–43) mmHg vs. 42 (37–47) mmHg, p = 0.03; pH: 7.41 (7.3–7.4) vs. 7.36 (7.3–7.4), p < 0.01). Multivariate linear regression modeling identified only hemoglobin as a predictor of altered rSO(2). Patients with a EuroScore II above 4% and an extended ICU stay were found to have lower rSO(2), while no difference was observed in patients with postoperative delirium or between the implanted valve types. Further prospective studies that eliminate differences in potential confounding variables are necessary to confirm the rise in rSO(2). Future research should provide more information on the value of cerebral oximetry for identifying high-risk patients who will require further clinical interventions in the setting of the TAVI procedure. MDPI 2022-03-30 /pmc/articles/PMC8999949/ /pubmed/35407537 http://dx.doi.org/10.3390/jcm11071930 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Schmidt, Götz Kreissl, Hannes Vigelius-Rauch, Ursula Schneck, Emmanuel Edinger, Fabian Nef, Holger Böning, Andreas Sander, Michael Koch, Christian Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study |
title | Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study |
title_full | Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study |
title_fullStr | Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study |
title_full_unstemmed | Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study |
title_short | Cerebral Tissue Oxygen Saturation Is Enhanced in Patients following Transcatheter Aortic Valve Implantation: A Retrospective Study |
title_sort | cerebral tissue oxygen saturation is enhanced in patients following transcatheter aortic valve implantation: a retrospective study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999949/ https://www.ncbi.nlm.nih.gov/pubmed/35407537 http://dx.doi.org/10.3390/jcm11071930 |
work_keys_str_mv | AT schmidtgotz cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT kreisslhannes cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT vigeliusrauchursula cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT schneckemmanuel cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT edingerfabian cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT nefholger cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT boningandreas cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT sandermichael cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy AT kochchristian cerebraltissueoxygensaturationisenhancedinpatientsfollowingtranscatheteraorticvalveimplantationaretrospectivestudy |