No association between APOE genotype and lipid lowering with cognitive function in a randomized controlled trial of evolocumab

APOE encodes a cholesterol transporter, and the ε4 allele is associated with higher circulating cholesterol levels, ß-amyloid burden, and risk of Alzheimer’s disease. Prior studies demonstrated no significant differences in objective or subjective cognitive function for patients receiving the PCSK9...

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Detalles Bibliográficos
Autores principales: Korthauer, Laura E., Giugliano, Robert P., Guo, Jianping, Sabatine, Marc S., Sever, Peter, Keech, Anthony, Atar, Dan, Kurtz, Christopher, Ruff, Christian T., Mach, Francois, Ott, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000128/
https://www.ncbi.nlm.nih.gov/pubmed/35404972
http://dx.doi.org/10.1371/journal.pone.0266615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000128/
https://www.ncbi.nlm.nih.gov/pubmed/35404972
http://dx.doi.org/10.1371/journal.pone.0266615

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