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Analysis of localized cAMP perturbations within a tissue reveal the effects of a local, dynamic gap junction state on ERK signaling

Beyond natural stimuli such as growth factors and stresses, the ability to experimentally modulate at will the levels or activity of specific intracellular signaling molecule(s) in specified cells within a tissue can be a powerful tool for uncovering new regulation and tissue behaviors. Here we pert...

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Detalles Bibliográficos
Autores principales: Fonseca, João Pedro, Aslankoohi, Elham, Ng, Andrew H., Chevalier, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000136/
https://www.ncbi.nlm.nih.gov/pubmed/35353814
http://dx.doi.org/10.1371/journal.pcbi.1009873