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Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases
The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein to its cellular receptor, the angiotensin-converting enzyme 2 (ACE2), causes its downregulation, which subsequently leads to the dysregulation of the renin–angiotensin system (RAS) in favor of the ACE–...
Autores principales: | El-Arif, George, Khazaal, Shaymaa, Farhat, Antonella, Harb, Julien, Annweiler, Cédric, Wu, Yingliang, Cao, Zhijian, Kovacic, Hervé, Abi Khattar, Ziad, Fajloun, Ziad, Sabatier, Jean-Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000463/ https://www.ncbi.nlm.nih.gov/pubmed/35408447 http://dx.doi.org/10.3390/molecules27072048 |
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