Inhibition of Aldose Reductase by Ginsenoside Derivatives via a Specific Structure Activity Relationship with Kinetics Mechanism and Molecular Docking Study

This present work is designed to evaluate the anti-diabetic potential of 22 ginsenosides via the inhibition against rat lens aldose reductase (RLAR), and human recombinant aldose reductase (HRAR), using (DL)-glyceraldehyde as a substrate. Among the ginsenosides tested, ginsenoside Rh2, (20S) ginseno...

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Detalles Bibliográficos
Autores principales: Ali, Md Yousof, Zaib, Sumera, Jannat, Susoma, Khan, Imtiaz, Rahman, M. Mizanur, Park, Seong Kyu, Chang, Mun Seog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000482/
https://www.ncbi.nlm.nih.gov/pubmed/35408532
http://dx.doi.org/10.3390/molecules27072134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000482/
https://www.ncbi.nlm.nih.gov/pubmed/35408532
http://dx.doi.org/10.3390/molecules27072134

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