Ligand and Structure-Based In Silico Determination of the Most Promising SARS-CoV-2 nsp16-nsp10 2′-o-Methyltransferase Complex Inhibitors among 3009 FDA Approved Drugs

As a continuation of our earlier work against SARS-CoV-2, seven FDA-approved drugs were designated as the best SARS-CoV-2 nsp16-nsp10 2′-o-methyltransferase (2′OMTase) inhibitors through 3009 compounds. The in silico inhibitory potential of the examined compounds against SARS-CoV-2 nsp16-nsp10 2′-o-...

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Detalles Bibliográficos
Autores principales: Eissa, Ibrahim H., Alesawy, Mohamed S., Saleh, Abdulrahman M., Elkaeed, Eslam B., Alsfouk, Bshra A., El-Attar, Abdul-Aziz M. M., Metwaly, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000629/
https://www.ncbi.nlm.nih.gov/pubmed/35408684
http://dx.doi.org/10.3390/molecules27072287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000629/
https://www.ncbi.nlm.nih.gov/pubmed/35408684
http://dx.doi.org/10.3390/molecules27072287

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