Prediction of Low-Dose Aspirin-Induced Gastric Toxicity Using Nuclear Magnetic Resonance Spectroscopy-Based Pharmacometabolomics in Rats

Background: Low-dose aspirin (LDA) is the backbone for secondary prevention of coronary artery disease, although limited by gastric toxicity. This study aimed to identify novel metabolites that could predict LDA-induced gastric toxicity using pharmacometabolomics. Methods: Pre-dosed urine samples we...

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Detalles Bibliográficos
Autores principales: Sha’aban, Abubakar, Zainal, Hadzliana, Khalil, Nor Azlina, Abd Aziz, Fatimatuzzahra’, Ch’ng, Ewe Seng, Teh, Chin-Hoe, Mohammed, Mustapha, Ibrahim, Baharudin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000689/
https://www.ncbi.nlm.nih.gov/pubmed/35408523
http://dx.doi.org/10.3390/molecules27072126

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