Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones

An efficient synthesis of a series of pyridazino[4,3-c:5,6-c′]diquinolines was achieved via the autoxidation of 4-hydrazinylquinolin-2(1H)-ones. IR, NMR ((1)H and (13)C), mass spectral data, and elemental analysis were used to fit and elucidate the structures of the newly synthesized compounds. X-ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Mostafa, Sara M., Aly, Ashraf A., Hassan, Alaa A., Osman, Esraa M., Bräse, Stefan, Nieger, Martin, Ibrahim, Mahmoud A. A., Mohamed, Asmaa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000902/
https://www.ncbi.nlm.nih.gov/pubmed/35408525
http://dx.doi.org/10.3390/molecules27072125
_version_ 1784685551722430464
author Mostafa, Sara M.
Aly, Ashraf A.
Hassan, Alaa A.
Osman, Esraa M.
Bräse, Stefan
Nieger, Martin
Ibrahim, Mahmoud A. A.
Mohamed, Asmaa H.
author_facet Mostafa, Sara M.
Aly, Ashraf A.
Hassan, Alaa A.
Osman, Esraa M.
Bräse, Stefan
Nieger, Martin
Ibrahim, Mahmoud A. A.
Mohamed, Asmaa H.
author_sort Mostafa, Sara M.
collection PubMed
description An efficient synthesis of a series of pyridazino[4,3-c:5,6-c′]diquinolines was achieved via the autoxidation of 4-hydrazinylquinolin-2(1H)-ones. IR, NMR ((1)H and (13)C), mass spectral data, and elemental analysis were used to fit and elucidate the structures of the newly synthesized compounds. X-ray structure analysis and theoretical calculations unequivocally proved the formation of the structure. The possible mechanism for the reaction is also discussed.
format Online
Article
Text
id pubmed-9000902
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-90009022022-04-12 Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones Mostafa, Sara M. Aly, Ashraf A. Hassan, Alaa A. Osman, Esraa M. Bräse, Stefan Nieger, Martin Ibrahim, Mahmoud A. A. Mohamed, Asmaa H. Molecules Article An efficient synthesis of a series of pyridazino[4,3-c:5,6-c′]diquinolines was achieved via the autoxidation of 4-hydrazinylquinolin-2(1H)-ones. IR, NMR ((1)H and (13)C), mass spectral data, and elemental analysis were used to fit and elucidate the structures of the newly synthesized compounds. X-ray structure analysis and theoretical calculations unequivocally proved the formation of the structure. The possible mechanism for the reaction is also discussed. MDPI 2022-03-25 /pmc/articles/PMC9000902/ /pubmed/35408525 http://dx.doi.org/10.3390/molecules27072125 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mostafa, Sara M.
Aly, Ashraf A.
Hassan, Alaa A.
Osman, Esraa M.
Bräse, Stefan
Nieger, Martin
Ibrahim, Mahmoud A. A.
Mohamed, Asmaa H.
Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones
title Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones
title_full Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones
title_fullStr Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones
title_full_unstemmed Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones
title_short Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones
title_sort autoxidation of 4-hydrazinylquinolin-2(1h)-one; synthesis of pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5h,8h)-diones
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000902/
https://www.ncbi.nlm.nih.gov/pubmed/35408525
http://dx.doi.org/10.3390/molecules27072125
work_keys_str_mv AT mostafasaram autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones
AT alyashrafa autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones
AT hassanalaaa autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones
AT osmanesraam autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones
AT brasestefan autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones
AT niegermartin autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones
AT ibrahimmahmoudaa autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones
AT mohamedasmaah autoxidationof4hydrazinylquinolin21honesynthesisofpyridazino43c56cdiquinoline675h8hdiones

Ejemplares similares