Cargando…

Oral Mucosa Derived α−Synuclein as a Potential Diagnostic Biomarker for Parkinson′s Disease

BACKGROUND: Pathological α-synuclein (α-Syn) is not only exclusive to the central nervous system (CNS) in Parkinson’s disease (PD), but also extended to biofluids and peripheral tissues including oral cavity. Both oral mucosa and nervous system are derived from ectodermal tissue, and potentially sha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Yuanchu, Yu, Zhenwei, Zhao, Jiajia, Cai, Huihui, Wang, Zhan, Wang, Xuemei, Feng, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000972/ https://www.ncbi.nlm.nih.gov/pubmed/35418851 http://dx.doi.org/10.3389/fnagi.2022.867528

Ejemplares similares

Alpha-Synuclein species in oral mucosa as potential biomarkers for multiple system atrophy
por: Zheng, Yuanchu, et al.
Publicado: (2022)

Erythrocytic α-Synuclein Species for Parkinson’s Disease Diagnosis and the Correlations With Clinical Characteristics
por: Yu, Zhenwei, et al.
Publicado: (2022)

Freezing of gait in Parkinson’s disease is associated with the microstructural and functional changes of globus pallidus internus
por: Kou, Wenyi, et al.
Publicado: (2022)

Erythrocytic alpha-synuclein as potential biomarker for the differentiation between essential tremor and Parkinson’s disease
por: Yu, Zhenwei, et al.
Publicado: (2023)

Biomarkers and the Role of α-Synuclein in Parkinson’s Disease
por: Du, Tingting, et al.
Publicado: (2021)

Aβ1-42-containing platelet-derived extracellular vesicle is associated with cognitive decline in Parkinson’s disease
por: Wang, Ziyu, et al.
Publicado: (2023)

Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease
por: Bridi, Jessika C., et al.
Publicado: (2018)

Editorial: Biomarkers and Pathogenesis of Alpha-Synuclein in Parkinson's Disease
por: Li, Puyu, et al.
Publicado: (2021)

α-synuclein pathogenesis in hiPSC models of Parkinson’s disease
por: Baena-Montes, Jara M., et al.
Publicado: (2021)

The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson’s disease
por: Smith, Jessica K., et al.
Publicado: (2023)

Proteostasis of α-Synuclein and Its Role in the Pathogenesis of Parkinson’s Disease
por: Han, Deqiang, et al.
Publicado: (2020)

Differential Diagnosis of Multiple System Atrophy-Parkinsonism and Parkinson's Disease Using α-Synuclein and External Anal Sphincter Electromyography
por: Cao, Zhentang, et al.
Publicado: (2020)

Plasma Levels of α-Synuclein, Aβ-40 and T-tau as Biomarkers to Predict Cognitive Impairment in Parkinson’s Disease
por: Chen, Nai-Ching, et al.
Publicado: (2020)

Increased DJ-1 and α-Synuclein in Plasma Neural-Derived Exosomes as Potential Markers for Parkinson’s Disease
por: Zhao, Zhen-Hua, et al.
Publicado: (2019)

Lipids as Trans-Acting Effectors for α-Synuclein in the Pathogenesis of Parkinson’s Disease
por: Ikenaka, Kensuke, et al.
Publicado: (2019)

α-Synuclein and Noradrenergic Modulation of Immune Cells in Parkinson’s Disease Pathogenesis
por: Butkovich, Laura M., et al.
Publicado: (2018)

The Roles of Post-translational Modifications on α-Synuclein in the Pathogenesis of Parkinson’s Diseases
por: Zhang, Jiaming, et al.
Publicado: (2019)

LRRK2 and α-Synuclein: Distinct or Synergistic Players in Parkinson’s Disease?
por: O’Hara, Darren M., et al.
Publicado: (2020)

Voltage-Gated Calcium Channels and α-Synuclein: Implications in Parkinson’s Disease
por: Leandrou, Emmanouela, et al.
Publicado: (2019)

Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson’s Disease Pathology
por: Yuan, Xin, et al.
Publicado: (2022)

Alpha-Synuclein as a Biomarker of Parkinson’s Disease: Good, but Not Good Enough
por: Ganguly, Upasana, et al.
Publicado: (2021)

Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson’s Disease
por: Pons, Marie-Laure, et al.
Publicado: (2022)

α-Synuclein Reactive Antibodies as Diagnostic Biomarkers in Blood Sera of Parkinson's Disease Patients
por: Yanamandra, Kiran, et al.
Publicado: (2011)

Erythrocytic α-Synuclein as a potential biomarker for Parkinson’s disease
por: Tian, Chen, et al.
Publicado: (2019)

Commentary: Discriminating α-synuclein strains in parkinson's disease and multiple system atrophy
por: Fellner, Lisa, et al.
Publicado: (2020)

Dynamics of a model for the degradation mechanism of aggregated α-synuclein in Parkinson's disease
por: Yang, Bojie, et al.
Publicado: (2023)

Anionic nanoplastic contaminants promote Parkinson’s disease–associated α-synuclein aggregation
por: Liu, Zhiyong, et al.
Publicado: (2023)

α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis
por: Wang, Pan, et al.
Publicado: (2023)

Versatile Structures of α-Synuclein
por: Wang, Chuchu, et al.
Publicado: (2016)

New Perspectives on Roles of Alpha-Synuclein in Parkinson’s Disease
por: Zhang, Guoxin, et al.
Publicado: (2018)

Inflammatory Responses to Monomeric and Aggregated α-Synuclein in Peripheral Blood of Parkinson Disease Patients
por: Piancone, Federica, et al.
Publicado: (2021)

The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson’s disease
por: Meng, Lanxia, et al.
Publicado: (2023)

Plasma α‐synuclein and phosphorylated tau 181 as a diagnostic biomarker panel for de novo Parkinson’s disease
por: Ren, Jingru, et al.
Publicado: (2022)

α-Synuclein-containing erythrocytic extracellular vesicles: essential contributors to hyperactivation of monocytes in Parkinson’s disease
por: Liu, Zongran, et al.
Publicado: (2022)

Can Interactions Between α-Synuclein, Dopamine and Calcium Explain Selective Neurodegeneration in Parkinson's Disease?
por: Post, Michael R., et al.
Publicado: (2018)

Elevated Serum α-Synuclein Autoantibodies in Patients with Parkinson’s Disease Relative to Alzheimer’s Disease and Controls
por: Shalash, Ali, et al.
Publicado: (2017)

Development of α-Synuclein Real-Time Quaking-Induced Conversion as a Diagnostic Method for α-Synucleinopathies
por: Nakagaki, Takehiro, et al.
Publicado: (2021)

Differential Circulating Levels of Naturally Occurring Antibody to α-Synuclein in Parkinson’s Disease Dementia, Alzheimer’s Disease, and Vascular Dementia
por: Wang, Jian, et al.
Publicado: (2020)

The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons
por: Anderson, Eric N., et al.
Publicado: (2020)

Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson’s Disease
por: Bellucci, Arianna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_aag2ih8i0ma3f4o71oj8k86qdn