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Protective Effects of Interleukin-37 Expression against Acetaminophen-Induced Hepatotoxicity in Mice

AIM: Interleukin (IL)-37 is a new anti-inflammatory cytokine of the IL-1 family. This study aimed to determine the effects of IL-37 on acetaminophen (APAP)-induced liver injury. MATERIALS AND METHODS: IL-37 plasmids were injected into mice via a tail vein hydrodynamics-based gene delivery. RESULTS:...

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Detalles Bibliográficos
Autores principales: Xu, Zhiwei, Li, Kan, Pan, Xiuhe, Tan, Jun, Li, Yan, Li, Mingcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001104/
https://www.ncbi.nlm.nih.gov/pubmed/35419070
http://dx.doi.org/10.1155/2022/6468299