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Pan-Caspase Inhibitor zVAD Induces Necroptotic and Autophagic Cell Death in TLR3/4-Stimulated Macrophages

In addition to inducing apoptosis, caspase inhibition contributes to necroptosis and/or autophagy depending on the cell type and cellular context. In macrophages, necroptosis can be induced by co-treatment with Toll-like receptor (TLR) ligands (lipopolysaccharide [LPS] for TLR4 and polyinosinic-poly...

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Detalles Bibliográficos
Autores principales:	Chen, Yuan-Shen, Chuang, Wei-Chu, Kung, Hsiu-Ni, Cheng, Ching-Yuan, Huang, Duen-Yi, Sekar, Ponarulselvam, Lin, Wan-Wan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001149/ https://www.ncbi.nlm.nih.gov/pubmed/34949739 http://dx.doi.org/10.14348/molcells.2021.0193

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