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NEDD9 sustains hexokinase expression to promote glycolysis
Elevated rates of glycolysis in cancer cells support tumor growth, in a process that typically depends on oncogene-induced increases in the expression and/or activity of enzymes in the glycolytic pathway. The NEDD9 scaffolding protein is upregulated in many advanced tumors, with increased NEDD9 prom...
Autores principales: | Deneka, Alexander Y., Nikonova, Anna S., Lee, Hyung-Ok, Kruger, Warren D., Golemis, Erica A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001639/ https://www.ncbi.nlm.nih.gov/pubmed/35410460 http://dx.doi.org/10.1038/s41389-022-00391-w |
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