CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma

As the first rate-limiting enzyme in fatty acid oxidation (FAO), CPT1 plays a significant role in metabolic adaptation in cancer pathogenesis. FAO provides an alternative energy supply for cancer cells and is required for cancer cell survival. Given the high proliferation rate of cancer cells, nucle...

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Detalles Bibliográficos
Autores principales: Tang, Min, Dong, Xin, Xiao, Lanbo, Tan, Zheqiong, Luo, Xiangjian, Yang, Lifang, Li, Wei, Shi, Feng, Li, Yueshuo, Zhao, Lin, Liu, Na, Du, Qianqian, Xie, Longlong, Hu, Jianmin, Weng, Xinxian, Fan, Jia, Zhou, Jian, Gao, Qiang, Wu, Weizhong, Zhang, Xin, Liao, Weihua, Bode, Ann M., Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001659/
https://www.ncbi.nlm.nih.gov/pubmed/35411000
http://dx.doi.org/10.1038/s41419-022-04730-y

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