Cargando…

MFSD4A inhibits the malignant progression of nasopharyngeal carcinoma by targeting EPHA2

DNA Methylation can lead to abnormal gene expression. In the present study, we investigated whether the expression of methylated MFSD4A (major facilitator superfamily domain containing 4 A) was downregulated in nasopharyngeal carcinoma (NPC) and whether it is associated with malignant progression an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Huiyun, Qin, Guanjie, Luo, Zan, Kong, Xiangyun, Gan, Chunqiao, Zhang, Ruyun, Jiang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001682/ https://www.ncbi.nlm.nih.gov/pubmed/35410462 http://dx.doi.org/10.1038/s41419-022-04793-x

Ejemplares similares

Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability
por: Lekholm, Emilia, et al.
Publicado: (2017)

The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake
por: Perland, Emelie, et al.
Publicado: (2016)

Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice
por: Perland, Emelie, et al.
Publicado: (2017)

The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis
por: Perland, Emelie, et al.
Publicado: (2016)

Correction: Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice
por: Perland, Emelie, et al.
Publicado: (2018)

Child Head Circumference and Placental MFSD2a Expression Are Associated to the Level of MFSD2a in Maternal Blood During Pregnancy
por: Sánchez-Campillo, María, et al.
Publicado: (2020)

A mechanism study of DUSP1 in inhibiting malignant progression of endometrial carcinoma by regulating ERK/AP-1 axis and dephosphorylation of EPHA2
por: Lei, Shu, et al.
Publicado: (2023)

MFSD12 mediates the import of cysteine into melanosomes and lysosomes
por: Adelmann, Charles H., et al.
Publicado: (2020)

The Role of Mfsd2a in Nervous System Diseases
por: Huang, Bei, et al.
Publicado: (2021)

Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by Shp2/Erk-1/2 signaling pathway
por: Xiang, Yi-Ping, et al.
Publicado: (2020)

Deletion of Mfsd2b impairs thrombotic functions of platelets
por: Chandrakanthan, Madhuvanthi, et al.
Publicado: (2021)

MFSD12 affects glycosphingolipid metabolism by modulating lysosome homeostasis
por: Hong, Yun, et al.
Publicado: (2022)

Methylation‐associated silencing of miR‐9‐1 promotes nasopharyngeal carcinoma progression and glycolysis via HK2
por: Xu, Qian‐Lan, et al.
Publicado: (2021)

Novel MFSD8 Variants in a Chinese Family with Nonsyndromic Macular Dystrophy
por: Xiang, Qin, et al.
Publicado: (2021)

EPHA2, EPHA4, and EPHA7 Expression in Triple-Negative Breast Cancer
por: Nikas, Ilias, et al.
Publicado: (2022)

LncRNA FOXD3-AS1 Promotes the Malignant Progression of Nasopharyngeal Carcinoma Through Enhancing the Transcription of YBX1 by H3K27Ac Modification
por: Yang, Huiyun, et al.
Publicado: (2021)

HDAC7 promotes the oncogenicity of nasopharyngeal carcinoma cells by miR-4465-EphA2 signaling axis
por: Li, Qi-Guang, et al.
Publicado: (2020)

Aberrant miR-362-3p is Associated with EBV-Infection and Prognosis in Nasopharyngeal Carcinoma and Involved in Tumor Progression by Targeting JMJD2A
por: Wang, Xiangyun, et al.
Publicado: (2022)

EPHA2, EPHA4, and EPHA6 Expression in Uveal Melanomas: Searching for the Culprits of Neoplasia
por: Pergaris, Alexandros, et al.
Publicado: (2022)

A Dimerized HMX1 Inhibits EPHA6/epha4b in Mouse and Zebrafish Retinas
por: Marcelli, Fabienne, et al.
Publicado: (2014)

Mfsd2a(+) hepatocytes repopulate the liver during injury and regeneration
por: Pu, Wenjuan, et al.
Publicado: (2016)

The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain
por: Chan, Jia Pei, et al.
Publicado: (2018)

The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis
por: Wong, Bernice H., et al.
Publicado: (2022)

Unveiling the role of Mfsd2a and LPC-DHA in kidney repair
por: Rietjens, Rosalie G.J., et al.
Publicado: (2023)

Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression
por: Li, Shibao, et al.
Publicado: (2017)

Loss of Cirbp expression is correlated with the malignant progression and poor prognosis in nasopharyngeal carcinoma
por: Lin, Tao-Yan, et al.
Publicado: (2019)

Inhibition of EphA3 Expression in Tumour Stromal Cells Suppresses Tumour Growth and Progression
por: Vail, Mary E., et al.
Publicado: (2023)

MFSD2B is a sphingosine 1-phosphate transporter in erythroid cells
por: Kobayashi, Naoki, et al.
Publicado: (2018)

MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme
por: Li, Yingzhong, et al.
Publicado: (2020)

Mfsd8 Modulates Growth and the Early Stages of Multicellular Development in Dictyostelium discoideum
por: Yap, Shyong Quan, et al.
Publicado: (2022)

Targeting EphA2 in cancer
por: Xiao, Ta, et al.
Publicado: (2020)

Linc01513 inhibits the malignant potential of Nasopharyngeal carcinoma by binding to PTBP1
por: Wang, Juan, et al.
Publicado: (2021)

Super Enhancer Driven Hyaluronan Synthase 3 Promotes Malignant Progression of Nasopharyngeal Carcinoma
por: Chen, Quanzhu, et al.
Publicado: (2023)

MiR-34b-3 and miR-449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A
por: Li, Huiling, et al.
Publicado: (2016)

Clinicopathologic characteristics of second primary squamous cell carcinoma in patients with nasopharyngeal carcinoma after intensity-modulated radiotherapy
por: Wang, Xi, et al.
Publicado: (2023)

TET2 suppresses nasopharyngeal carcinoma progression by inhibiting glycolysis metabolism
por: Zhang, Xixia, et al.
Publicado: (2020)

Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer’s Disease
por: Sánchez-Campillo, María, et al.
Publicado: (2019)

Frameshift Variant in MFSD12 Explains the Mushroom Coat Color Dilution in Shetland Ponies
por: Tanaka, Jocelyn, et al.
Publicado: (2019)

Extracellular Vesicles in the Progression and Therapeutic Resistance of Nasopharyngeal Carcinoma
por: Shan, Yunhan, et al.
Publicado: (2022)

EphA5 and EphA6: regulation of neuronal and spine morphology
por: Das, Gitanjali, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rl072ja0a2ema2dbt1edvcijr0