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Organocatalytic atroposelective construction of axially chiral N, N- and N, S-1,2-azoles through novel ring formation approach

1,2-Azoles are privileged structures in ligand/catalyst design and widely exist in many important natural products and drugs. In this report, two types of axially chiral 1,2-azoles (naphthyl-isothiazole S-oxides with a stereogenic sulfur center and atropoisomeric naphthyl pyrazoles) are synthesized...

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Detalles Bibliográficos
Autores principales: Chang, Yu, Xie, Chuandong, Liu, Hong, Huang, Shengli, Wang, Pengfei, Qin, Wenling, Yan, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001698/
https://www.ncbi.nlm.nih.gov/pubmed/35410417
http://dx.doi.org/10.1038/s41467-022-29557-1