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Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers

The pancreas is a central organ for human diseases. Most alleles uncovered by genome-wide association studies of pancreatic dysfunction traits overlap with non-coding sequences of DNA. Many contain epigenetic marks of cis-regulatory elements active in pancreatic cells, suggesting that alterations in...

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Detalles Bibliográficos
Autores principales:	Bordeira-Carriço, Renata, Teixeira, Joana, Duque, Marta, Galhardo, Mafalda, Ribeiro, Diogo, Acemel, Rafael D., Firbas, Panos. N., Tena, Juan J., Eufrásio, Ana, Marques, Joana, Ferreira, Fábio J., Freitas, Telmo, Carneiro, Fátima, Goméz-Skarmeta, José Luís, Bessa, José
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001708/ https://www.ncbi.nlm.nih.gov/pubmed/35410466 http://dx.doi.org/10.1038/s41467-022-29551-7

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