Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature

Acquired hepatocerebral degeneration (AHD) is a neurologic syndrome caused by liver dysfunction and long-standing portosystemic shunting. The pathogenesis of the condition is predominantly considered to be related to the deposition of manganese in parts of the brain due to shunting. We report a case...

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Autores principales: Mohammed, Abdu, Bane, Abate, Mengistu, Getahun, Ayalew, Fekadu, Seid, Amir Sultan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001859/
https://www.ncbi.nlm.nih.gov/pubmed/35464550
http://dx.doi.org/10.7759/cureus.23064
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author Mohammed, Abdu
Bane, Abate
Mengistu, Getahun
Ayalew, Fekadu
Seid, Amir Sultan
author_facet Mohammed, Abdu
Bane, Abate
Mengistu, Getahun
Ayalew, Fekadu
Seid, Amir Sultan
author_sort Mohammed, Abdu
collection PubMed
description Acquired hepatocerebral degeneration (AHD) is a neurologic syndrome caused by liver dysfunction and long-standing portosystemic shunting. The pathogenesis of the condition is predominantly considered to be related to the deposition of manganese in parts of the brain due to shunting. We report a case of a 25-year-old male who underwent splenectomy and splenorenal shunt for recurrent upper GI bleeding (UGIB) due to esophageal varices caused by non-cirrhotic portal hypertension (NCPH). He presented with bradykinesia, hypophonia, gait instability, and rigidity of the lower extremities 18 months after the procedure was done.
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spelling pubmed-90018592022-04-23 Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature Mohammed, Abdu Bane, Abate Mengistu, Getahun Ayalew, Fekadu Seid, Amir Sultan Cureus Internal Medicine Acquired hepatocerebral degeneration (AHD) is a neurologic syndrome caused by liver dysfunction and long-standing portosystemic shunting. The pathogenesis of the condition is predominantly considered to be related to the deposition of manganese in parts of the brain due to shunting. We report a case of a 25-year-old male who underwent splenectomy and splenorenal shunt for recurrent upper GI bleeding (UGIB) due to esophageal varices caused by non-cirrhotic portal hypertension (NCPH). He presented with bradykinesia, hypophonia, gait instability, and rigidity of the lower extremities 18 months after the procedure was done. Cureus 2022-03-11 /pmc/articles/PMC9001859/ /pubmed/35464550 http://dx.doi.org/10.7759/cureus.23064 Text en Copyright © 2022, Mohammed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Mohammed, Abdu
Bane, Abate
Mengistu, Getahun
Ayalew, Fekadu
Seid, Amir Sultan
Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature
title Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature
title_full Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature
title_fullStr Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature
title_full_unstemmed Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature
title_short Acquired Hepatocerebral Degeneration After a Splenorenal Shunt in the Sub-Saharan Africa Context: A Case Report and Brief Review of Literature
title_sort acquired hepatocerebral degeneration after a splenorenal shunt in the sub-saharan africa context: a case report and brief review of literature
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001859/
https://www.ncbi.nlm.nih.gov/pubmed/35464550
http://dx.doi.org/10.7759/cureus.23064
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