Cargando…

Whole-genome sequence analysis through online web interfaces: a review

The recent development of whole-genome sequencing technologies paved the way for understanding the genomes of microorganisms. Every whole-genome sequencing (WGS) project requires a considerable cost and a massive effort to address the questions at hand. The final step of WGS is data analysis. The an...

Descripción completa

Detalles Bibliográficos
Autores principales: Gunasekara, A. W. A. C. W. R., Rajapaksha, L. G. T. G., Tung, T.L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002002/
https://www.ncbi.nlm.nih.gov/pubmed/35399002
http://dx.doi.org/10.5808/gi.20038
_version_ 1784685798007767040
author Gunasekara, A. W. A. C. W. R.
Rajapaksha, L. G. T. G.
Tung, T.L
author_facet Gunasekara, A. W. A. C. W. R.
Rajapaksha, L. G. T. G.
Tung, T.L
author_sort Gunasekara, A. W. A. C. W. R.
collection PubMed
description The recent development of whole-genome sequencing technologies paved the way for understanding the genomes of microorganisms. Every whole-genome sequencing (WGS) project requires a considerable cost and a massive effort to address the questions at hand. The final step of WGS is data analysis. The analysis of whole-genome sequence is dependent on highly sophisticated bioinformatics tools that the research personal have to buy. However, many laboratories and research institutions do not have the bioinformatics capabilities to analyze the genomic data and therefore, are unable to take maximum advantage of whole-genome sequencing. In this aspect, this study provides a guide for research personals on a set of bioinformatics tools available online that can be used to analyze whole-genome sequence data of bacterial genomes. The web interfaces described here have many advantages and, in most cases exempting the need for costly analysis tools and intensive computing resources.
format Online
Article
Text
id pubmed-9002002
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Korea Genome Organization
record_format MEDLINE/PubMed
spelling pubmed-90020022022-04-21 Whole-genome sequence analysis through online web interfaces: a review Gunasekara, A. W. A. C. W. R. Rajapaksha, L. G. T. G. Tung, T.L Genomics Inform Review Article The recent development of whole-genome sequencing technologies paved the way for understanding the genomes of microorganisms. Every whole-genome sequencing (WGS) project requires a considerable cost and a massive effort to address the questions at hand. The final step of WGS is data analysis. The analysis of whole-genome sequence is dependent on highly sophisticated bioinformatics tools that the research personal have to buy. However, many laboratories and research institutions do not have the bioinformatics capabilities to analyze the genomic data and therefore, are unable to take maximum advantage of whole-genome sequencing. In this aspect, this study provides a guide for research personals on a set of bioinformatics tools available online that can be used to analyze whole-genome sequence data of bacterial genomes. The web interfaces described here have many advantages and, in most cases exempting the need for costly analysis tools and intensive computing resources. Korea Genome Organization 2022-03-31 /pmc/articles/PMC9002002/ /pubmed/35399002 http://dx.doi.org/10.5808/gi.20038 Text en (c) 2022, Korea Genome Organization https://creativecommons.org/licenses/by/4.0/(CC) This is an open-access article distributed under the terms of the Creative Commons Attribution license(https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Gunasekara, A. W. A. C. W. R.
Rajapaksha, L. G. T. G.
Tung, T.L
Whole-genome sequence analysis through online web interfaces: a review
title Whole-genome sequence analysis through online web interfaces: a review
title_full Whole-genome sequence analysis through online web interfaces: a review
title_fullStr Whole-genome sequence analysis through online web interfaces: a review
title_full_unstemmed Whole-genome sequence analysis through online web interfaces: a review
title_short Whole-genome sequence analysis through online web interfaces: a review
title_sort whole-genome sequence analysis through online web interfaces: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002002/
https://www.ncbi.nlm.nih.gov/pubmed/35399002
http://dx.doi.org/10.5808/gi.20038
work_keys_str_mv AT gunasekaraawacwr wholegenomesequenceanalysisthroughonlinewebinterfacesareview
AT rajapakshalgtg wholegenomesequenceanalysisthroughonlinewebinterfacesareview
AT tungtl wholegenomesequenceanalysisthroughonlinewebinterfacesareview