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In Vitro and In Vivo Studies for the Investigation of γ-Globin Gene Induction by Adhatoda vasica: A Pre-Clinical Study of HbF Inducers for β-Thalassemia

Fetal hemoglobin (HbF) is a potent genetic modifier, and the γ-globin gene induction has proven to be a sustainable therapeutic approach for the management of β-thalassemia. In this study, we have evaluated the HbF induction ability of A. vasica in vitro and in vivo, and the identification of potent...

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Detalles Bibliográficos
Autores principales:	Iftikhar, Fizza, Rahman, Saeedur, Khan, Muhammad Behroz Naeem, Khan, Kanwal, Khan, Muhammad Noman, Uddin, Reaz, Musharraf, Syed Ghulam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002120/ https://www.ncbi.nlm.nih.gov/pubmed/35422700 http://dx.doi.org/10.3389/fphar.2022.797853

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