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Valproic acid enhances neurosphere formation in cultured rat embryonic cortical cells through TGFβ1 signaling

This study aimed to investigate the effect and mechanism of valproic acid (VPA) on the neurosphere formation in rat embryonic cortical cells. We used free-floating neurosphere formation as a model system to evaluate the VPA on the proliferation of neural stem cells (NSCs). We found a time- and dose-...

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Detalles Bibliográficos
Autores principales: Qi, Cui, Zhang, Jiaqi, Wang, Yuanyuan, Lin, Mingyan, Gao, Jun, Lu, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002158/
https://www.ncbi.nlm.nih.gov/pubmed/35387900
http://dx.doi.org/10.7555/JBR.36.20210109