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Exchange of a Single Amino Acid Residue in the HybG Chaperone Allows Maturation of All H(2)-Activating [NiFe]-Hydrogenases in Escherichia coli

The biosynthesis of the NiFe(CN)(2)CO organometallic cofactor of [NiFe]-hydrogenase (Hyd) involves several discreet steps, including the synthesis of the Fe(CN)(2)CO group on a HypD-HypC scaffold complex. HypC has an additional function in transferring the Fe(CN)(2)CO group to the apo-precursor of t...

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Detalles Bibliográficos
Autores principales: Haase, Alexander, Sawers, R. Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002611/
https://www.ncbi.nlm.nih.gov/pubmed/35422773
http://dx.doi.org/10.3389/fmicb.2022.872581