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Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection
Surface-enhanced Raman spectroscopy (SERS) has long been an ultrasensitive technique for trace molecule detection. However, the development of a sensitive, stable, and reproducible SERS substrate is still a challenge for practical applications. Here, we demonstrate a cost-effective, centimeter-sized...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002873/ https://www.ncbi.nlm.nih.gov/pubmed/35407320 http://dx.doi.org/10.3390/nano12071202 |
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author | Wang, Zhenming Liu, Jianxun Wang, Jiawei Ma, Zongjun Kong, Delai Jiang, Shouzhen Luo, Dan Liu, Yan Jun |
author_facet | Wang, Zhenming Liu, Jianxun Wang, Jiawei Ma, Zongjun Kong, Delai Jiang, Shouzhen Luo, Dan Liu, Yan Jun |
author_sort | Wang, Zhenming |
collection | PubMed |
description | Surface-enhanced Raman spectroscopy (SERS) has long been an ultrasensitive technique for trace molecule detection. However, the development of a sensitive, stable, and reproducible SERS substrate is still a challenge for practical applications. Here, we demonstrate a cost-effective, centimeter-sized, and highly reproducible SERS substrate using the nanosphere lithography technique. It consists of a hexagonally packed Ag metasurface on a SiO(2)/Au/Si substrate. A seconds-lasting etching process of a self-assembled nanosphere mask manipulates the geometry of the deposited Ag metasurface on the SiO(2)/Au/Si substrate, which attains the wavelength matching between the optical absorbance of the Ag/SiO(2)/Au/Si substrate and the excitation laser wavelength as well as the enhancement of Raman signals. By spin-coating a thin layer of graphene oxide on the substrate, a SERS performance with 1.1 × 10(5) analytical enhancement factor and a limit of detection of 10(−9) M for melamine is achieved. Experimental results reveal that our proposed strategy could provide a promising platform for SERS-based rapid trace detection in food safety control and environmental monitoring. |
format | Online Article Text |
id | pubmed-9002873 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90028732022-04-13 Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection Wang, Zhenming Liu, Jianxun Wang, Jiawei Ma, Zongjun Kong, Delai Jiang, Shouzhen Luo, Dan Liu, Yan Jun Nanomaterials (Basel) Article Surface-enhanced Raman spectroscopy (SERS) has long been an ultrasensitive technique for trace molecule detection. However, the development of a sensitive, stable, and reproducible SERS substrate is still a challenge for practical applications. Here, we demonstrate a cost-effective, centimeter-sized, and highly reproducible SERS substrate using the nanosphere lithography technique. It consists of a hexagonally packed Ag metasurface on a SiO(2)/Au/Si substrate. A seconds-lasting etching process of a self-assembled nanosphere mask manipulates the geometry of the deposited Ag metasurface on the SiO(2)/Au/Si substrate, which attains the wavelength matching between the optical absorbance of the Ag/SiO(2)/Au/Si substrate and the excitation laser wavelength as well as the enhancement of Raman signals. By spin-coating a thin layer of graphene oxide on the substrate, a SERS performance with 1.1 × 10(5) analytical enhancement factor and a limit of detection of 10(−9) M for melamine is achieved. Experimental results reveal that our proposed strategy could provide a promising platform for SERS-based rapid trace detection in food safety control and environmental monitoring. MDPI 2022-04-03 /pmc/articles/PMC9002873/ /pubmed/35407320 http://dx.doi.org/10.3390/nano12071202 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Zhenming Liu, Jianxun Wang, Jiawei Ma, Zongjun Kong, Delai Jiang, Shouzhen Luo, Dan Liu, Yan Jun Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection |
title | Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection |
title_full | Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection |
title_fullStr | Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection |
title_full_unstemmed | Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection |
title_short | Graphene Oxide-Coated Metal–Insulator–Metal SERS Substrates for Trace Melamine Detection |
title_sort | graphene oxide-coated metal–insulator–metal sers substrates for trace melamine detection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002873/ https://www.ncbi.nlm.nih.gov/pubmed/35407320 http://dx.doi.org/10.3390/nano12071202 |
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