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Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter

Fetal electrocardiogram (fECG) assessment is essential throughout pregnancy to monitor the wellbeing and development of the fetus, and to possibly diagnose potential congenital heart defects. Due to the high noise incorporated in the abdominal ECG (aECG) signals, the extraction of fECG has been chal...

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Autores principales: Sarafan, Sadaf, Le, Tai, Lau, Michael P. H., Hameed, Afshan, Ghirmai, Tadesse, Cao, Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003129/
https://www.ncbi.nlm.nih.gov/pubmed/35408402
http://dx.doi.org/10.3390/s22072788
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author Sarafan, Sadaf
Le, Tai
Lau, Michael P. H.
Hameed, Afshan
Ghirmai, Tadesse
Cao, Hung
author_facet Sarafan, Sadaf
Le, Tai
Lau, Michael P. H.
Hameed, Afshan
Ghirmai, Tadesse
Cao, Hung
author_sort Sarafan, Sadaf
collection PubMed
description Fetal electrocardiogram (fECG) assessment is essential throughout pregnancy to monitor the wellbeing and development of the fetus, and to possibly diagnose potential congenital heart defects. Due to the high noise incorporated in the abdominal ECG (aECG) signals, the extraction of fECG has been challenging. And it is even a lot more difficult for fECG extraction if only one channel of aECG is provided, i.e., in a compact patch device. In this paper, we propose a novel algorithm based on the Ensemble Kalman filter (EnKF) for non-invasive fECG extraction from a single-channel aECG signal. To assess the performance of the proposed algorithm, we used our own clinical data, obtained from a pilot study with 10 subjects each of 20 min recording, and data from the PhysioNet 2013 Challenge bank with labeled QRS complex annotations. The proposed methodology shows the average positive predictive value (PPV) of 97.59%, sensitivity (SE) of 96.91%, and F1-score of 97.25% from the PhysioNet 2013 Challenge bank. Our results also indicate that the proposed algorithm is reliable and effective, and it outperforms the recently proposed extended Kalman filter (EKF) based algorithm.
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spelling pubmed-90031292022-04-13 Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter Sarafan, Sadaf Le, Tai Lau, Michael P. H. Hameed, Afshan Ghirmai, Tadesse Cao, Hung Sensors (Basel) Article Fetal electrocardiogram (fECG) assessment is essential throughout pregnancy to monitor the wellbeing and development of the fetus, and to possibly diagnose potential congenital heart defects. Due to the high noise incorporated in the abdominal ECG (aECG) signals, the extraction of fECG has been challenging. And it is even a lot more difficult for fECG extraction if only one channel of aECG is provided, i.e., in a compact patch device. In this paper, we propose a novel algorithm based on the Ensemble Kalman filter (EnKF) for non-invasive fECG extraction from a single-channel aECG signal. To assess the performance of the proposed algorithm, we used our own clinical data, obtained from a pilot study with 10 subjects each of 20 min recording, and data from the PhysioNet 2013 Challenge bank with labeled QRS complex annotations. The proposed methodology shows the average positive predictive value (PPV) of 97.59%, sensitivity (SE) of 96.91%, and F1-score of 97.25% from the PhysioNet 2013 Challenge bank. Our results also indicate that the proposed algorithm is reliable and effective, and it outperforms the recently proposed extended Kalman filter (EKF) based algorithm. MDPI 2022-04-05 /pmc/articles/PMC9003129/ /pubmed/35408402 http://dx.doi.org/10.3390/s22072788 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sarafan, Sadaf
Le, Tai
Lau, Michael P. H.
Hameed, Afshan
Ghirmai, Tadesse
Cao, Hung
Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter
title Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter
title_full Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter
title_fullStr Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter
title_full_unstemmed Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter
title_short Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter
title_sort fetal electrocardiogram extraction from the mother’s abdominal signal using the ensemble kalman filter
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003129/
https://www.ncbi.nlm.nih.gov/pubmed/35408402
http://dx.doi.org/10.3390/s22072788
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