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Trifluoromethylated Pyrazoles via Sequential (3 + 2)-Cycloaddition of Fluorinated Nitrile Imines with Chalcones and Solvent-Dependent Deacylative Oxidation Reactions

[Image: see text] A general approach for preparation of two types of polyfunctionalized 3-trifluoromethylpyrazoles is reported. The protocol comprises (3 + 2)-cycloaddition of the in situ generated trifluoroacetonitrile imines with enones leading to trans-configured 5-acyl-pyrazolines in a fully reg...

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Detalles Bibliográficos
Autores principales:	Kowalczyk, Anna, Utecht-Jarzyńska, Greta, Mlostoń, Grzegorz, Jasiński, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003577/ https://www.ncbi.nlm.nih.gov/pubmed/35343703 http://dx.doi.org/10.1021/acs.orglett.2c00521

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