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Molecular mechanism by which CDCP1 promotes proneural-mesenchymal transformation in primary glioblastoma
BACKGROUND: Compared with the proneural (PN) subtype of glioblastoma (GBM), the mesenchymal (MES) subtype is more invasive and immune evasive and is closely related to poor prognosis. Here, we used transcriptome data and experimental evidence to indicate that CUB domain-containing protein 1 (CDCP1)...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003964/ https://www.ncbi.nlm.nih.gov/pubmed/35410293 http://dx.doi.org/10.1186/s12935-021-02373-1 |