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Molecular mechanism by which CDCP1 promotes proneural-mesenchymal transformation in primary glioblastoma

BACKGROUND: Compared with the proneural (PN) subtype of glioblastoma (GBM), the mesenchymal (MES) subtype is more invasive and immune evasive and is closely related to poor prognosis. Here, we used transcriptome data and experimental evidence to indicate that CUB domain-containing protein 1 (CDCP1)...

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Detalles Bibliográficos
Autores principales:	Lin, Zhiying, Zhang, Zhu, Zheng, Haojie, Xu, Haiyan, Wang, Yajuan, Chen, Chao, Liu, Junlu, Yi, Guozhong, Li, Zhiyong, Wang, Xiaoyan, Huang, Guanglong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003964/ https://www.ncbi.nlm.nih.gov/pubmed/35410293 http://dx.doi.org/10.1186/s12935-021-02373-1

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