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Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report

BACKGROUND: Rhabdomyolysis is a serious and potentially life threatening condition that can be caused by drugs. We report a case of acute hepatitis B with rhabdomyolysis after treatment with rosuvastatin and entecavir. CASE PRESENTATION: A 72-year-old female was admitted to our hospital due to acute...

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Autores principales: Wang, Wen, Lu, Xu, Li, Chengbo, Teng, Wei, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004004/
https://www.ncbi.nlm.nih.gov/pubmed/35410138
http://dx.doi.org/10.1186/s12879-022-07254-0
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author Wang, Wen
Lu, Xu
Li, Chengbo
Teng, Wei
Cui, Wei
author_facet Wang, Wen
Lu, Xu
Li, Chengbo
Teng, Wei
Cui, Wei
author_sort Wang, Wen
collection PubMed
description BACKGROUND: Rhabdomyolysis is a serious and potentially life threatening condition that can be caused by drugs. We report a case of acute hepatitis B with rhabdomyolysis after treatment with rosuvastatin and entecavir. CASE PRESENTATION: A 72-year-old female was admitted to our hospital due to acute hepatitis B infection. She had taken atorvastatin for 3 months before being admitted to our hospital. After being administered entecavir (ETV) and rosuvastatin to replace atorvastatin, she suffered from muscle pain in both lower limbs and was diagnosed with rhabdomyolysis. After discontinuation of the two drugs, the patient's symptoms subsided and creatine kinase levels returned to normal. We hypothesize that the rhabdomyolysis was caused by the combination of rosuvastatin and ETV. CONCLUSIONS: We suggest that patients who use rosuvastatin and ETV be made aware of the complication of rhabdomyolysis.
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spelling pubmed-90040042022-04-13 Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report Wang, Wen Lu, Xu Li, Chengbo Teng, Wei Cui, Wei BMC Infect Dis Case Report BACKGROUND: Rhabdomyolysis is a serious and potentially life threatening condition that can be caused by drugs. We report a case of acute hepatitis B with rhabdomyolysis after treatment with rosuvastatin and entecavir. CASE PRESENTATION: A 72-year-old female was admitted to our hospital due to acute hepatitis B infection. She had taken atorvastatin for 3 months before being admitted to our hospital. After being administered entecavir (ETV) and rosuvastatin to replace atorvastatin, she suffered from muscle pain in both lower limbs and was diagnosed with rhabdomyolysis. After discontinuation of the two drugs, the patient's symptoms subsided and creatine kinase levels returned to normal. We hypothesize that the rhabdomyolysis was caused by the combination of rosuvastatin and ETV. CONCLUSIONS: We suggest that patients who use rosuvastatin and ETV be made aware of the complication of rhabdomyolysis. BioMed Central 2022-04-11 /pmc/articles/PMC9004004/ /pubmed/35410138 http://dx.doi.org/10.1186/s12879-022-07254-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Wang, Wen
Lu, Xu
Li, Chengbo
Teng, Wei
Cui, Wei
Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
title Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
title_full Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
title_fullStr Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
title_full_unstemmed Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
title_short Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
title_sort rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004004/
https://www.ncbi.nlm.nih.gov/pubmed/35410138
http://dx.doi.org/10.1186/s12879-022-07254-0
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