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Salt-inducible kinase 2 (SIK2) inhibitor ARN-3236 attenuates bleomycin-induced pulmonary fibrosis in mice

BACKGROUND: Pulmonary fibrosis is a fatal lung disease with complex pathogenesis and limited effective therapies. Salt-inducible kinase 2 (SIK2) is a kinase that phosphorylates CRTCs and regulates many physiological processes. However, the role of SIK2 on pulmonary fibrosis remains unclear, and whet...

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Detalles Bibliográficos
Autores principales:	Zou, Liangneng, Hong, Dequn, Li, Kecong, Jiang, Bingyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004037/ https://www.ncbi.nlm.nih.gov/pubmed/35410283 http://dx.doi.org/10.1186/s12890-022-01940-0

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