Cysteine-rich protein 2 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in mice

BACKGROUND: Abdominal aortic aneurysm (AAA) is a relatively common and often fatal condition. A major histopathological hallmark of AAA is the severe degeneration of aortic media with loss of vascular smooth muscle cells (VSMCs), which are the main source of extracellular matrix (ECM) proteins. VSMC...

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Detalles Bibliográficos
Autores principales: Chen, Chung-Huang, Ho, Hua-Hui, Jiang, Wei-Cheng, Ao-Ieong, Wai-Sam, Wang, Jane, Orekhov, Alexander N., Sobenin, Igor A., Layne, Matthew D., Yet, Shaw-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004090/
https://www.ncbi.nlm.nih.gov/pubmed/35414069
http://dx.doi.org/10.1186/s12929-022-00808-z

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