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Allostery‐driven changes in dynamics regulate the activation of bacterial copper transcription factor

Metalloregulators bind and respond to metal ions by regulating the transcription of metal homeostasis genes. Copper efflux regulator (CueR) is a copper‐responsive metalloregulator that is found in numerous Gram‐negative bacteria. Upon Cu(I) coordination, CueR initiates transcription by bending the b...

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Detalles Bibliográficos
Autores principales: Yakobov, Idan, Mandato, Alysia, Hofmann, Lukas, Singewald, Kevin, Shenberger, Yulia, Gevorkyan‐Airapetov, Lada, Saxena, Sunil, Ruthstein, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004249/
https://www.ncbi.nlm.nih.gov/pubmed/35481642
http://dx.doi.org/10.1002/pro.4309

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